MARC details
000 -LEADER |
fixed length control field |
05411naaaa2201297uu 4500 |
001 - CONTROL NUMBER |
control field |
https://directory.doabooks.org/handle/20.500.12854/69154 |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20220714193825.0 |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
books978-3-03936-737-5 |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9783039367368 |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9783039367375 |
024 7# - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.3390/books978-3-03936-737-5 |
Terms of availability |
doi |
041 0# - LANGUAGE CODE |
Language code of text/sound track or separate title |
English |
042 ## - AUTHENTICATION CODE |
Authentication code |
dc |
072 #7 - SUBJECT CATEGORY CODE |
Subject category code |
M |
Source |
bicssc |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
LU, Kun |
Relator code |
edt |
9 (RLIN) |
1620156 |
245 10 - TITLE STATEMENT |
Title |
Biomarkers of Environmental Toxicants |
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
Place of publication, distribution, etc |
Basel, Switzerland |
Name of publisher, distributor, etc |
MDPI - Multidisciplinary Digital Publishing Institute |
Date of publication, distribution, etc |
2020 |
300 ## - PHYSICAL DESCRIPTION |
Extent |
1 electronic resource (292 p.) |
506 0# - RESTRICTIONS ON ACCESS NOTE |
Terms governing access |
Open Access |
Source of term |
star |
Standardized terminology for access restriction |
Unrestricted online access |
520 ## - SUMMARY, ETC. |
Summary, etc |
Biomarkers of environmental toxicants are measures of exposures, some of which can serve to assess disease risk and inter-individual susceptibilities. Metabolites, protein and DNA adducts also serve to elucidate the mechanisms of the bioactivation and detoxication of reactive toxicant intermediates. Some environmental chemicals act as modulators of gene and protein activity, and induce the dysbiosis of the microbiome, which impacts the metabolome and overall health. In this Special Issue on "Biomarkers of Environmental Toxicants", review articles and original research studies are featured, covering the latest bioanalytical, biochemical and mass spectrometry-based technologies, to monitor exposures through targeted and non-targeted methods, and mechanistic studies that examine the biological effects of environmental toxicants in cells and humans. Diverse topics, such as exposome, microbiome, DNA/protein adducts and t-RNA modifications, as well as important environment toxicants, including heavy metals, benzene, phthalates, aldehydes, glycidol, tobacco smoke and aristolochic acids, are covered. Novel analytical methods, such as protein adductomics, DNA adduct analysis in formalin-fixed paraffin-embedded tissues, site-specific mutagenesis assay and accelerator mass spectrometry, are also included. This collection provides a valuable update of the most recent biochemical and analytical tools that employ biomarkers in toxicology research, biomarker discovery, and exposure and risk assessment in population-based studies. |
540 ## - TERMS GOVERNING USE AND REPRODUCTION NOTE |
Terms governing use and reproduction |
Creative Commons |
-- |
https://creativecommons.org/licenses/by/4.0/ |
-- |
cc |
-- |
https://creativecommons.org/licenses/by/4.0/ |
546 ## - LANGUAGE NOTE |
Language note |
English |
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name as entry element |
Medicine |
Source of heading or term |
bicssc |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
manganese |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
lead |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
cadmium |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
arsenic |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
hair |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
children |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
environment |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
carcinogen |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
DNA adducts |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
biomonitoring |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
formalin-fixed paraffin-embedded tissues |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
biomarker |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
mass spectrometry |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
human biomonitoring |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
urine |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
non-occupational exposure |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
S-phenyl-mercapturic acid |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
HPLC-MS/MS |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
glycidol |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Hb adduct |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
N-(2.3-dihydroxypropyl)valine |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
in vivo |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
cancer risk |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
UPLC/MS/MS |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
aristolochic acids |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
food contamination |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
environmental pollution |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
root uptake |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
aristolochic acid nephropathy |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
Balkan endemic nephropathy |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
chronic kidney disease |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
tobacco smoke |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
human carcinogen |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
biomarkers |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
epitranscriptomics |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
tRNA modifications |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
stress response mechanisms |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
codon-biased translation |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
phthalate |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
DEHP |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
human exposure |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
toxicity |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
reproductive |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
accelerator mass spectrometry |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
cavity ring down spectrophotometry |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
radiocarbon |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
naphthalene |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
benzo[a]pyrene |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
cell turnover |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
triclocarban |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
metastasis |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
haemoglobin |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
albumin |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
protein adducts |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
aldehydes |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
genotoxicity |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
cancer |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
diseases |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
oxidative stress |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
exposure biomarkers |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
high-resolution mass spectrometry |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
data-dependent profiling |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
derivatization |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
biological fluids |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
isotope labeling |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
DNA lesion |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
DNA damage |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
shuttle vector technique |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
replication block |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
mutagenicity |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
mutational spectrum |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
mutational signature |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
DNA repair |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
DNA adduct bypass |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
site-specific mutagenesis |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
chemical exposome |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
environmental monitoring |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
disease |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
bioinformatics |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
gut microbiome |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
chemical toxicity |
653 ## - INDEX TERM--UNCONTROLLED |
Uncontrolled term |
n/a |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Turesky, Robert J. |
Relator code |
edt |
9 (RLIN) |
1620157 |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
LU, Kun |
Relator code |
oth |
9 (RLIN) |
1620156 |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Turesky, Robert J. |
Relator code |
oth |
9 (RLIN) |
1620157 |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Host name |
www.oapen.org |
Uniform Resource Identifier |
<a href="https://mdpi.com/books/pdfview/book/2926">https://mdpi.com/books/pdfview/book/2926</a> |
-- |
0 |
Public note |
DOAB: download the publication |
856 40 - ELECTRONIC LOCATION AND ACCESS |
Host name |
www.oapen.org |
Uniform Resource Identifier |
<a href="https://directory.doabooks.org/handle/20.500.12854/69154">https://directory.doabooks.org/handle/20.500.12854/69154</a> |
-- |
0 |
Public note |
DOAB: description of the publication |