000			03384naaaa2200733uu 4500
001			https://directory.doabooks.org/handle/20.500.12854/53247
005			20220714185546.0
020			_a9783038428442
020			_a9783038428435
041	0		_aEnglish
042			_adc
100	1		_aReinhard Dallinger (Ed.) _4auth _91608555
245	1	0	_aMetal Metabolism in Animals
260			_bMDPI - Multidisciplinary Digital Publishing Institute _c2018
300			_a1 electronic resource (X, 356 p.)
506	0		_aOpen Access _2star _fUnrestricted online access
520			_aThrough evolution of life, animals have adapted to the ubiquitous presence of metals in the biosphere. They utilize the more frequent ones as essential constituents of their biochemical machinery. In fact, about 40% of all proteins present in animal cells are so-called metalloproteins. On the other hand, animals have invented regulatory and detoxifying mechanisms to protect themselves from critical concentrations of both essential and non-essential metal concentrations. Metallomics is a modern approach applying cellular, biochemical, molecular and analytical methods to investigate the relationships of metals in their cellular context. The present edition contains a number of original articles and reviews dealing with various aspects of metallomics in animals, published as Special Issues of the International Journal of Molecular Sciences in 2016 and 2017. The book addresses subjects such as metal definition in biology, metabolism of metals in invertebrate and vertebrate animals, metal detoxification and regulation strategies, supplementation of essential trace elements, metal behavior in pregnancy and embryonic development, as well as metal toxicology and emerging medical implications.
540			_aCreative Commons _fhttps://creativecommons.org/licenses/by-nc-nd/4.0/ _2cc _4https://creativecommons.org/licenses/by-nc-nd/4.0/
546			_aEnglish
653			_aAllergy
653			_aProtein Biochemistry
653			_aOxidative Stress
653			_aMetalloprotein
653			_aHomeostasis
653			_aMetal Uptake
653			_aIron
653			_aMetal
653			_aSynthase
653			_aImmunity
653			_aAccumulation
653			_aModel Organism
653			_aMethylmercury
653			_aDevelopment
653			_aMetal Toxicity
653			_aEssential Trace Element
653			_aCopper
653			_aProtection
653			_aMolecular Methods
653			_aMetal Supplementation
653			_aBinding Specificity
653			_aCadmium
653			_aTransgenic Organisms
653			_aT Cells
653			_aNon-Essential Trace Element
653			_aAnimal Model
653			_aHypersensitivity
653			_aDetoxification
653			_aTolerance
653			_aHistology
653			_aPalladium
653			_aMetalloenzyme
653			_aStress
653			_aZinc
653			_aRegulation
653			_aNickel
653			_aProtein Disease
653			_aMercury
653			_aPhytochelatin
653			_aMetallothionein
653			_aApoptosis
653			_aCancer
856	4	0	_awww.oapen.org _uhttp://www.mdpi.com/books/pdfview/book/588 _70 _zDOAB: download the publication
856	4	0	_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/53247 _70 _zDOAB: description of the publication
999			_c3008641 _d3008641