000 | 02415naaaa2200325uu 4500 | ||
---|---|---|---|
001 | https://directory.doabooks.org/handle/20.500.12854/54590 | ||
005 | 20220714184049.0 | ||
020 | _a978-2-88919-988-4 | ||
020 | _a9782889199884 | ||
024 | 7 |
_a10.3389/978-2-88919-988-4 _cdoi |
|
041 | 0 | _aEnglish | |
042 | _adc | ||
100 | 1 |
_aA. Murat Eren _4auth _91604654 |
|
700 | 1 |
_aMitchell Sogin _4auth _91604655 |
|
700 | 1 |
_aLois Maignien _4auth _91604656 |
|
245 | 1 | 0 | _aNew Insights into Microbial Ecology through Subtle Nucleotide Variation |
260 |
_bFrontiers Media SA _c2016 |
||
300 | _a1 electronic resource (133 p.) | ||
506 | 0 |
_aOpen Access _2star _fUnrestricted online access |
|
520 | _aThe 16S ribosomal RNA gene commonly serves as a molecular marker for investigating microbial community composition and structure. Vast amounts of 16S rRNA amplicon data generated from environmental samples thanks to the recent advances in sequencing technologies allowed microbial ecologists to explore microbial community dynamics over temporal and spatial scales deeper than ever before. However, widely used methods for the analysis of bacterial communities generally ignore subtle nucleotide variations among high-throughput sequencing reads and often fail to resolve ecologically meaningful differences between closely related organisms in complex microbial datasets. Lack of proper partitioning of the sequencing data into relevant units often masks important ecological patterns. Our research topic contains articles that use oligotyping to demonstrate the importantance of high-resolution analyses of marker gene data, and providides further evidence why microbial ecologists should open the "black box" of OTUs identified through arbitrary sequence similarity thresholds. | ||
540 |
_aCreative Commons _fhttps://creativecommons.org/licenses/by/4.0/ _2cc _4https://creativecommons.org/licenses/by/4.0/ |
||
546 | _aEnglish | ||
653 | _ahigh-resolution | ||
653 | _aoligotyping | ||
653 | _aMinimum Entropy Decomposition | ||
653 | _amicrobiome | ||
653 | _a16S rRNA gene | ||
856 | 4 | 0 |
_awww.oapen.org _uhttp://journal.frontiersin.org/researchtopic/2427/new-insights-into-microbial-ecology-through-subtle-nucleotide-variation _70 _zDOAB: download the publication |
856 | 4 | 0 |
_awww.oapen.org _uhttps://directory.doabooks.org/handle/20.500.12854/54590 _70 _zDOAB: description of the publication |
999 |
_c3005422 _d3005422 |