000 02415naaaa2200325uu 4500
001 https://directory.doabooks.org/handle/20.500.12854/54590
005 20220714184049.0
020 _a978-2-88919-988-4
020 _a9782889199884
024 7 _a10.3389/978-2-88919-988-4
_cdoi
041 0 _aEnglish
042 _adc
100 1 _aA. Murat Eren
_4auth
_91604654
700 1 _aMitchell Sogin
_4auth
_91604655
700 1 _aLois Maignien
_4auth
_91604656
245 1 0 _aNew Insights into Microbial Ecology through Subtle Nucleotide Variation
260 _bFrontiers Media SA
_c2016
300 _a1 electronic resource (133 p.)
506 0 _aOpen Access
_2star
_fUnrestricted online access
520 _aThe 16S ribosomal RNA gene commonly serves as a molecular marker for investigating microbial community composition and structure. Vast amounts of 16S rRNA amplicon data generated from environmental samples thanks to the recent advances in sequencing technologies allowed microbial ecologists to explore microbial community dynamics over temporal and spatial scales deeper than ever before. However, widely used methods for the analysis of bacterial communities generally ignore subtle nucleotide variations among high-throughput sequencing reads and often fail to resolve ecologically meaningful differences between closely related organisms in complex microbial datasets. Lack of proper partitioning of the sequencing data into relevant units often masks important ecological patterns. Our research topic contains articles that use oligotyping to demonstrate the importantance of high-resolution analyses of marker gene data, and providides further evidence why microbial ecologists should open the "black box" of OTUs identified through arbitrary sequence similarity thresholds.
540 _aCreative Commons
_fhttps://creativecommons.org/licenses/by/4.0/
_2cc
_4https://creativecommons.org/licenses/by/4.0/
546 _aEnglish
653 _ahigh-resolution
653 _aoligotyping
653 _aMinimum Entropy Decomposition
653 _amicrobiome
653 _a16S rRNA gene
856 4 0 _awww.oapen.org
_uhttp://journal.frontiersin.org/researchtopic/2427/new-insights-into-microbial-ecology-through-subtle-nucleotide-variation
_70
_zDOAB: download the publication
856 4 0 _awww.oapen.org
_uhttps://directory.doabooks.org/handle/20.500.12854/54590
_70
_zDOAB: description of the publication
999 _c3005422
_d3005422