000 | 04524cam a2200805Ia 4500 | ||
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001 | ocn795706882 | ||
003 | OCoLC | ||
005 | 20220711174319.0 | ||
006 | m o d | ||
007 | cr cnu---unuuu | ||
008 | 120618s2011 enka obf 000 0 eng d | ||
010 | _z 2012419417 | ||
040 |
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019 |
_a796384634 _a821643742 _a1053886424 _a1162207755 |
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020 |
_a9780199749751 _q(electronic bk.) |
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020 |
_a0199749752 _q(electronic bk.) |
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020 | _a1280699094 | ||
020 | _a9781280699092 | ||
020 | _z9780199735679 | ||
020 | _z0199735670 | ||
020 | _a9786613676061 | ||
020 | _a6613676063 | ||
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050 | 4 |
_aRC280.B8 _bB87 2011eb |
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060 | 4 | _aWP 900 | |
072 | 7 |
_aHEA _x039030 _2bisacsh |
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072 | 7 |
_aMED _x062000 _2bisacsh |
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082 | 0 | 4 |
_a616.99449061 _222 |
049 | _aMAIN | ||
100 | 1 |
_aBurstein, Harold J. _9877290 |
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245 | 1 | 0 |
_aTargeted therapies in breast cancer / _cHarold J. Burstein. |
260 |
_aOxford ; _aNew York : _bOxford University Press, _c©2011. |
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300 |
_a1 online resource (54 pages) : _billustrations |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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490 | 1 | _aOxford American pocket notes | |
504 | _aIncludes bibliographical references. | ||
588 | 0 | _aPrint version record. | |
505 | 0 | _aCover; Table of Contents; Introduction; Antiestrogen Therapies; Aromatase Inhibitors (AI's); Selective Estrogen Receptor Modulators (SERM's) and Estrogen-Receptor Downregulators (ERD's); Chemotherapeutic Agents-Microtubule Targeting Agents; Taxanes; Ixabepilone; Eribulin Mesylate; HER2 Directed Therapies for Metastatic Breast Cancer; Trastuzumab; Trastuzumab-Refactory Breast Cancer; Investigational Agents; HER2 Directed Therapy for Early Stage Breast Cancer; Angiogenesis Inhibitors in Breast Cancer; Bevacizumab; VEGFR Inhibitors; PARP Inhibitors; Emerging Areas; References. | |
520 | _aThe development of monoclonal antibodies and other inhibitors of specific molecules, fully utilizing the insights learned from molecular techniques such as comparative microarrays and protein expression patterns, has led to the development and FDA approval of several agents for the treatment of breast cancer, such as trastuzamab (Herceptin, targeting HER-2 positive tumors) and lapatinib (Tykerb, targeting tumors with mutated/overexpressed EGFR 1 and 2). Other agents specifically targeting the estrogen receptor, the aromatose pathway and microtubule dynamics, fulvestrant (Faslodex, targeting th. | ||
546 | _aEnglish. | ||
590 |
_aeBooks on EBSCOhost _bEBSCO eBook Subscription Academic Collection - Worldwide |
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650 | 0 |
_aBreast _xCancer _xTreatment _vHandbooks, manuals, etc. _9877291 |
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650 | 0 |
_aDrug targeting _vHandbooks, manuals, etc. _9877292 |
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650 | 2 |
_aDrug Delivery Systems _9165016 |
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650 | 2 |
_aBreast Neoplasms _xdrug therapy _9877293 |
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650 | 6 |
_aSein _xCancer _xTraitement _vGuides, manuels, etc. _9877294 |
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650 | 6 |
_aMédicaments _xCiblage _vGuides, manuels, etc. _9877295 |
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650 | 7 |
_aHEALTH & FITNESS _xDiseases _xCancer. _2bisacsh _9864670 |
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650 | 7 |
_aMEDICAL _xOncology. _2bisacsh _9864671 |
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650 | 7 |
_aBreast _xCancer _xTreatment. _2fast _0(OCoLC)fst00838313 _95390 |
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650 | 7 |
_aDrug targeting. _2fast _0(OCoLC)fst00898709 _9195392 |
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655 | 0 | _aElectronic books. | |
655 | 4 | _aElectronic books. | |
655 | 7 |
_aHandbooks and manuals. _2fast _0(OCoLC)fst01423877 _933825 |
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776 | 0 | 8 |
_iPrint version: _aBurstein, Harold J. _tTargeted therapies in breast cancer. _dOxford ; New York : Oxford University Press, ©2011 _z9780199735679 _w(DLC) 2012419417 _w(OCoLC)619903409 |
830 | 0 |
_aOxford American pocket notes. _9235290 |
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