Update on polymers for pulmonary drug delivery / Hugh D.C. Smyth, Ibrahim El-Sherbiny and Jason McConville.

Includes bibliographical references and index.

Pulmonary drug delivery has been a rapidly expanding field, moving from the traditional propellant based metered dose inhaler delivery of small asthma drugs, to a broader landscape of new devices and novel drugs for local and systemic delivery. The field has greatly expanded yet the tools for pulmonary drug delivery systems have not kept pace with the potential applications. One of the key developments has been the use of polymers to achieve better control of pulmonary drug delivery. This has the potential to expand the toolbox available for researchers in the field to deliver their new chemic.

Print version record.

9781847356550_Front Cover; 9781847356550_Contents; Preface; Contributors ; Chapter 01; 1 Pulmonary Drug Delivery, Concepts and Practice ; 1.1 History and Rationale of Pulmonary Drug Delivery ; 1.2 Diseases and Inhaled Products ; 1.2.1 Asthma ; 1.2.2 Chronic Obstructive Pulmonary Disease ; 1.2.3 Cystic Fibrosis ; 1.3 Rationale for Developing Polymer-based Pulmonary Delivery Systems ; 1.3.1 Drug Protection ; 1.3.2 Drug Release and Targeting ; 1.3.3 Vaccines [41] ; 1.4 Physiological Barriers to Lung Delivery ; 1.4.1 Aerodynamics ; 1.4.2 Mucociliary Clearance ; 1.4.3 Alveolar Macrophages.

1.4.4 Drug Absorption Rates 1.5 Summary ; References ; Chapter 02; 2 Polymers for Pulmonary Drug Delivery based on their Interactions with the Lung: Biodegradation, C; 2.1 Introduction ; 2.1.1 Rationale for the Use of Polymeric Carriers for Pulmonary Drug Delivery ; 2.1.2 Selection Criteria of a Polymeric Carrier for Inhalation Therapy ; 2.1.3 B.

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