DNA methylation : principles, mechanisms and challenges / Tatiana V. Tatarinova and Gaurav Sablok, editors.

Includes bibliographical references and index.

Description based on print version record.

DNA METHYLATION ; DNA METHYLATION; Contents ; Preface ; Introduction to DNA Methylation and Its Role in Carcinogenesis ; Abstract; 1. Introduction; 2. DNA Methyltransferases ; 3. DNA Demethylation; 4. DNA Methylation and Chromatin Structure ; 5. Mechanisms of Gene Suppression ; 6. Functions of DNA Methylation ; 7. Methylation and Carcinogenesis; DNA Hypomethylation in Cancer ; DNA Hypermethylation in Cancer ; Clinical Applications: Epigenetic Markers and Therapy; Conclusion ; Acknowledgment ; References ; DNA Methylation: A Cause or a Consequence of Gene Silencing? ; Abstract.

Introduction Establishment of New Patterns of DNA Methylation in Somatic Cells ; The Placement of DNA Methylation in the Sequence of Events Involved in Gene Silencing ; The Role of DNA Methylation during DNA Replication ; Conclusion ; Acknowledgment ; References ; The Role of DNA Methylation in Plants ; Abstract ; Introduction ; 2. DNA Methylation and Histone Modifications in Plants ; 2.1. DNA Methylation in Plants; 2.2. Histone Modifications and DNA Methylation; 3. DNA Methylation in Plant Development and Tissue ; 3.1. DNA Methylation Plays a Role in Plant Development.

3.2. Tissue Specificity of DNA Methylation4. DNA Methylation and Transposon Silencing; 5. Developmental Control of TransposableElements in Gametophytes and Seeds ; 6. Genomic Imprinting ; 6.1. Genomic Imprinting in Flowering Plants ; 6.2. Genomic Imprinting Contributing to the Reproductive Barrier ; 7. Natural Epigenetic Variation ; 8. Quantitative Epigenetics; Acknowledgments ; References ; Epigenetic Control of Circadian Clock Operation; Abstract ; Introduction ; 1. The Mammalian Clockwork; 1.1. Canonical Mammalian Clockwork Mechanisms.

1.2. Adjusting the Phase and Entrainment of the Cellular Clock1.3. Coupling of the Circadian Clock with Cellular Metabolism; 1.4. Hierarchical Organization of the Central and Peripheral Oscillators ; 1.5. Non-TTFL Mechanisms for Oscillatory Processes with a Circadian Period ; 2. Exceptions to the Omnipresence of Cellular Circadian Clocks ; 2.1. Interaction of the Circadian Clock with the Cell Cycle Machinery ; 2.2. Mouse Fetal Tissues-Uncertain Status of the Cellular Circadian Clock.

2.3. Embryonic Stem Cells and Induced Pluripotent Stem Cells: Lack of Circadian Oscillation at the Cellular Level 3. Possible Mechanisms for Lack of Cellular Circadian Oscillation ; 3.1. Epigenetic Misregulation of Clock Gene Expression ; 3.2. Metabolic Adaptations under Hypoxia and Immature Mitochondrial Energy Production in Proliferating Fetal Tissues ; Perspectives ; References ; Epigenetic Regulation of Photoperiodic Flowering ; Abstract ; 1. Introduction ; 2. Flowering Induced by azaC in Perilla Frutescens Var. Crispa ; 2.1. Stability of the Photoperiodically Induced Flowering State.

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