Advances in tissue engineering / editor, Julia Polak ; co-editors, Sakis Mantalaris, Sian E. Harding.

Includes bibliographical references and index.

Print version record.

Contributors; Foreword; Introduction; Part I: Tissue Engineering: Past, Present, and Future; Chapter 1: An Introduction Robert M. Nerem; 1. Introduction; 2. The Early Years; 3. The 1990s; 4. 2000 to Present; 5. What About the Future?; 6. Concluding Discussion; Acknowledgements; References; Part II: Cells for Tissue Engineering; Chapter 2: A Brief Introduction to Different Cell Types Lee Buttery and Kevin M. Shakesheff; 1. Introduction; 2. Cells and Tissue Engineering; 3. Mature or Primary Cells; 4. Stem Cells; 5. Sources of Stem Cells; 5.1. Adult (somatic) stem cells (ASC).

5.2. The adult stem cell niche5.3. Bone marrow stem cells; 5.4. Haematopoietic stem cells (HSCs); 5.5. Bone marrow stromal stem cells (BMSCs)/mesenchymal stem cells (MSCs); 5.6. Multipotent adult stem cells (MAPCs); 5.7. ASCs from other tissues; 5.8. Cord blood stem cells and foetal stem cells; 5.9. Embryonic stem cells; 5.10. Epiblast stem cells; 6. Immortalised Cell Lines; 7. Reprogramming; 8. Differentiation of Cells; 9. Regulatory Issues; 9.1. Cells; 9.2. Animal studies; References; Chapter 3: Human Embryonic Stem Cells: International Policy and Regulation Megan Allyse and Stephen Minger.

1. Introduction2. Controversy; 3. International Guidelines; 4. National Policy Systems; 4.1. India; 4.2. South Korea; 4.3. China; 4.4. United Kingdom; 4.5. United States; 5. Conclusion; References; Chapter 4: Human Embryonic Stem Cells: Derivation and Culture Emma L. Stephenson, Peter R. Braude and Chris Mason; 1. Introduction; 2. The Emergence of Human Embryonic Stem Cell Research; 2.1. Regulation of human embryo research; 3. Human Embryonic Stem Cells; 3.1. Definition; 3.2. Embryonic stem cell derivation methods; 3.2.1. Embryonic stem cells without the destruction of embryos.

3.3. Preimplantation genetic diagnosis and stem cell derivation4. Culture of hESC lines; 4.1. Feeder cells; 4.2. Media composition; 4.2.1. Oxygen tension; 5. Reporting of Derivation; 6. Concluding Remarks; References; Chapter 5: Stem Cells Differentiation Pascale V. Guillot and Wei Cui; 1. Introduction; 2. Differentiation of Embryonic Stem Cells; 3. Somatic Stem Cells; 3.1. Adult mesenchymal stem cells; 3.2. Foetal mesenchymal stem cells; 4. Conclusion; References; Chapter 6: Marrow Stem Cells Donald G. Phinney; 1. Introduction; 2. Hematopoietic Stem Cells: Discovery, Phenotype, and Function.

3. Mesenchymal Stem Cells: Discovery, Phenotype, and Function4. Endothelial Progenitor Cells: Discovery, Phenotype, and Function; 5. A Common Origin for Bone Marrow Stem Cells; 6. Functional Interdependency of Bone Marrow Stem Cells; 7. Summary; References; Chapter 7: Cord Blood Stem Cells -- Potentials and Realities Colin P. McGuckin and Nicolas Forraz; 1. Introduction to the Concept of Umbilical Cord Blood Stem Cells; 2. Cord Blood Current Clinical Uses; 3. Cord Blood Processing and Cryopreservation; 4. Cord Blood Banking; 5. Cord Blood Research and Where the Future Lies; References.

Advances in Tissue Engineering is a unique volume and the first of its kind to bring together leading names in the field of tissue engineering and stem cell research. A relatively young science, tissue engineering can be seen in both scientific and sociological contexts and successes in the field are now leading to clinical reality. This book attempts to define the path from basic science to practical application. A contribution from the UK Stem Cell Bank and opinions of venture capitalists offer a variety of viewpoints, and exciting new areas of stem cell biology are highlighted. With over fi.

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