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Perspectives in stem cell research / Brenda M. Davis and Christopher B. Halton, editors.

Contributor(s): Material type: TextTextSeries: Stem cells--laboratory and clinical research seriesPublisher: Hauppauge, N.Y. : Nova Science Publishers, [2011]Description: 1 online resourceContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9781620819937
  • 1620819937
Subject(s): Genre/Form: Additional physical formats: Print version:: Perspectives in stem cell researchDDC classification:
  • 616/.02774 22
LOC classification:
  • QH588.S83
Online resources:
Contents:
PERSPECTIVES IN STEM CELL RESEARCH; PERSPECTIVES IN STEM CELL RESEARCH ; CONTENTS ; PREFACE ; STEM CELL RESEARCH* ; SUMMARY ; OVERVIEW OF BASIC RESEARCH AND POTENTIAL APPLICATIONS ; Stem Cells from Embryos or Fetal Tissue ; Stem Cells from Adult Tissue or Umbilical Cord Blood ; Potential Applications of Stem Cell Research ; Current Federal Regulatory Landscape ; State Legislation on Embryonic Stem Cell Research ; Congressional Actions ; International Actions on Embryonic Stem Cell Research ; Ethical Issues ; REFERENCES ; CANCER STEM CELLS ; ABSTRACT ; INTRODUCTION ; STEM CELLS.
CANCER STEM CELLS ORIGIN OF CANCER STEM CELLS ; IDENTIFICATION AND ISOLATION OF CANCER STEM CELLS ; CANCER STEM CELL-TARGETED THERAPIES ; CONCLUSION ; REFERENCES ; PROSTATE STEM CELLS ; ABSTRACT ; THE PROSTATE GLAND ; Anatomy -- The Zonal Model of the Prostate ; Peripheral Zone ; Central Zone ; Transition Zone; Physiology of the Prostate ; PROSTATIC HYPERPLASIA AND CANCER ; Benign Prostatic Hyperplasia (BPH) ; Prostatic Intraepithelial Neoplasia ; Prostate Cancer ; ADULT STEM CELLS -- A SHORT HISTORY AND PROPERTIES ; Self-renewal of Stem Cells ; Pluripotency of Adult Stem Cells.
Techniques of Isolation of Adult Stem Cell from Tissues other than Prostate Isolation of Adult Stem Cells from the Prostate ; TUMOR INITIATING CELLS (TICS) FROM NORMAL HUMAN PROSTATE ; FUTURE PERSPECTIVES ; REFERENCES; MESENCHYMAL STEM CELLS IN VASCULAR THERAPY ; ABSTRACT ; I. INTRODUCTION ; II. WHAT IS A STEM CELL? ; A. Definitions and Ontogenesis ; B. Totipotent Stem Cells ; C. Pluripotent Stem Cells ; D. Multipotent Stem Cells; E. Unipotent Stem Cells; F. Between Differentiation and Self-Renewing: The Stem Cell Niche ; G. Stemness ; III. MESENCHYMAL STEM CELLS ; A. Origin.
1. Historical Identification 2. Source ; a) Various Species ; b) Tissue Localization ; c) Mobilization ; B. Culture ; 1. Isolation ; 2. CFU-F ; 3. A Heterogeneous Population ; 4. Phenotype ; C. Properties ; 1. Growth and Self-Renewing ; 2. The Bone Marrow Microenvironment and Hematopoiesis Support ; 3. Lineage Differentiation ; a) Mechanism ; b). Ectodermal Tissues ; c) Mesodermal Tissues; d) Endodermal Tissues ; 4. Immunosuppressive Properties ; D. Capacities ; 1. Homing and Domiciliation ; 2. Tissue Regeneration ; 3. Oxygen Sensing ; IV. VASCULAR THERAPIES ; A. The Normal Vessel.
B. Mesenchymal Stem Cells Implication in Vascular Remodeling 1. MSCs and the Smooth Muscle Differentiation ; a) Bone Marrow Stroma and Vascular Smooth Muscle Phenotype ; b) The Smooth Muscle Differentiation ; c) Markers of the Smooth Muscle Differentiation ; 2. MSCs and Endothelial Trans-Differentiation ; 3. Growth Factor Release and Paracrine Effects of MSCs ; C. Stem Cell Implication during Angiogenesis, Vasculogenesis and Arteriogenesis ; 1. Stem Cell Implication during Pulmonary Remodeling ; a) Mechanisms of the Pulmonary Vascular Development.
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Includes bibliographical references and index.

Description based on print version record.

PERSPECTIVES IN STEM CELL RESEARCH; PERSPECTIVES IN STEM CELL RESEARCH ; CONTENTS ; PREFACE ; STEM CELL RESEARCH* ; SUMMARY ; OVERVIEW OF BASIC RESEARCH AND POTENTIAL APPLICATIONS ; Stem Cells from Embryos or Fetal Tissue ; Stem Cells from Adult Tissue or Umbilical Cord Blood ; Potential Applications of Stem Cell Research ; Current Federal Regulatory Landscape ; State Legislation on Embryonic Stem Cell Research ; Congressional Actions ; International Actions on Embryonic Stem Cell Research ; Ethical Issues ; REFERENCES ; CANCER STEM CELLS ; ABSTRACT ; INTRODUCTION ; STEM CELLS.

CANCER STEM CELLS ORIGIN OF CANCER STEM CELLS ; IDENTIFICATION AND ISOLATION OF CANCER STEM CELLS ; CANCER STEM CELL-TARGETED THERAPIES ; CONCLUSION ; REFERENCES ; PROSTATE STEM CELLS ; ABSTRACT ; THE PROSTATE GLAND ; Anatomy -- The Zonal Model of the Prostate ; Peripheral Zone ; Central Zone ; Transition Zone; Physiology of the Prostate ; PROSTATIC HYPERPLASIA AND CANCER ; Benign Prostatic Hyperplasia (BPH) ; Prostatic Intraepithelial Neoplasia ; Prostate Cancer ; ADULT STEM CELLS -- A SHORT HISTORY AND PROPERTIES ; Self-renewal of Stem Cells ; Pluripotency of Adult Stem Cells.

Techniques of Isolation of Adult Stem Cell from Tissues other than Prostate Isolation of Adult Stem Cells from the Prostate ; TUMOR INITIATING CELLS (TICS) FROM NORMAL HUMAN PROSTATE ; FUTURE PERSPECTIVES ; REFERENCES; MESENCHYMAL STEM CELLS IN VASCULAR THERAPY ; ABSTRACT ; I. INTRODUCTION ; II. WHAT IS A STEM CELL? ; A. Definitions and Ontogenesis ; B. Totipotent Stem Cells ; C. Pluripotent Stem Cells ; D. Multipotent Stem Cells; E. Unipotent Stem Cells; F. Between Differentiation and Self-Renewing: The Stem Cell Niche ; G. Stemness ; III. MESENCHYMAL STEM CELLS ; A. Origin.

1. Historical Identification 2. Source ; a) Various Species ; b) Tissue Localization ; c) Mobilization ; B. Culture ; 1. Isolation ; 2. CFU-F ; 3. A Heterogeneous Population ; 4. Phenotype ; C. Properties ; 1. Growth and Self-Renewing ; 2. The Bone Marrow Microenvironment and Hematopoiesis Support ; 3. Lineage Differentiation ; a) Mechanism ; b). Ectodermal Tissues ; c) Mesodermal Tissues; d) Endodermal Tissues ; 4. Immunosuppressive Properties ; D. Capacities ; 1. Homing and Domiciliation ; 2. Tissue Regeneration ; 3. Oxygen Sensing ; IV. VASCULAR THERAPIES ; A. The Normal Vessel.

B. Mesenchymal Stem Cells Implication in Vascular Remodeling 1. MSCs and the Smooth Muscle Differentiation ; a) Bone Marrow Stroma and Vascular Smooth Muscle Phenotype ; b) The Smooth Muscle Differentiation ; c) Markers of the Smooth Muscle Differentiation ; 2. MSCs and Endothelial Trans-Differentiation ; 3. Growth Factor Release and Paracrine Effects of MSCs ; C. Stem Cell Implication during Angiogenesis, Vasculogenesis and Arteriogenesis ; 1. Stem Cell Implication during Pulmonary Remodeling ; a) Mechanisms of the Pulmonary Vascular Development.

English.

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