Immunopharmacology of free radical species / edited by David Blake and Paul G. Winyard.

Contributor(s):

Material type: Text

TextSeries: Handbook of immunopharmacology. Cells and mediators.Publication details: London ; San Diego : Academic Press, ©1995.Description: 1 online resource (xiii, 301 pages, 1 unnumbered leaf of plates) : illustrations (some color)Content type:

text

Media type:

computer

Carrier type:

online resource

ISBN:

9780121035204
0121035204
9780080534541
0080534546
1281076775
9781281076779

Subject(s):

Genre/Form:

Electronic books.

Additional physical formats: Print version:: Immunopharmacology of free radical species.DDC classification:

616.07 22

LOC classification:

RB170 .I44 1995eb

NLM classification:

QD 471 .I33 1995

Other classification:

KL 71

Online resources:

Click here to access online

Contents:

M. Grootveld and C.J. Rhodes, Methods for the Detection and Measurement of Reactive Radical Species in vivo and in Vitro. -- V.M. Darley-Usmar, R.P. Mason, W. Chamulitrat, N. Hogg, and B. Kalyanaraman, Lipid Peroxidation and Cardiovascular Disease. -- C. Rice-Evans, Free Radicals and Antioxidants in Atherosclerosis. -- M.J. Shattock and P.S. Haddock, Oxidant Stress and the Heart: Modulation of Ion Transport Mechanisms during Ischaemia and Reperfusion. -- J.A. Clemens and J.A. Panetta, Free Radicals in Central Nervous System Diseases. -- C.J. Green, Renal Transplantation and Ischaemia-Reperfusion Injury. -- M.L. Kus, K. Fairburn, D.R. Blake, and P.G. Winyard, A Vascular Basis for Free Radical Involvement in Inflammatory Joint Disease. -- C.J. Morris, C.W. Trenam, and J.R. Earl, Reactive Oxygen Species in Skin Inflammation. -- M. Goss-Sampson, A.J. Vivian, and F.J. Kelly, Free Radicals, Inflammation, and Eye Diseases. -- N.J. Simmonds, Free Radicals in Gastrointestinal and Hepatic Disease. -- M.J. Jackson, A. McArdle, and S. OFarrell, Free Radicals, Muscle Fatigue, and Damage. -- A.J. Sinclair and J. Lunec, Free Radicals, Oxidative Stress, and Diabetes Mellitus. -- O.I. Aruoma and B. Halliwell, DNA Damage by Free Radicals: Carcinogenic Implications. -- M. Yeadon, Free Radicals in Lung Inflammation and Environmental Exposure to Pollutants. -- K.H. Cheeseman, Free Radicals and Liver Injury. -- P.H. Evans, The Conioses: Organotypic Inflammatory Oxidative Responses to Environmental Particulate Pollutants. -- J.A. Panetta and J.M. McCall, Reactive Oxygen: Recent Therapeutic Intervention Strategies. -- Glossary. -- Subject Index.

Methods for the detection and measurement of reactive radical species in vivo and in vitro -- Lipid peroxidation and cardiovascular disease -- Free radicals and antioxidants in atherosclerosis -- Oxidant stress and the heart: modulation of ion transport mechanisms during ischaemia and reperfusion -- Free radicals in central nervous system diseases -- Renal transplantation and ischaemia-reperfusion injury -- Vascular basis for free radical involvement in inflammatory joint disease -- Reactive oxygen species in skin inflammation -- Free radicals, inflammation and eye diseases -- Free radicals in gastrointestinal and hepatic disease -- Free radicals, muscle fatigue and damage -- Free radicals, oxidative stress and diabetes mellitus -- DNA damage by free radicals: carcinogenic implications -- Free radicals in lung inflammation and environmental exposure to pollutants -- Free radicals and liver injury -- Conioses: organotypic inflammatory oxidative responses to environmental particulate pollutants -- Reactive oxygen: recent therapeutic intervention strategies.

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digitized 2010 HathiTrust Digital Library committed to preserve

Summary: Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recentyears, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is theperturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing fromthis new knowledge.

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Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recentyears, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is theperturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing fromthis new knowledge.

Includes bibliographical references and index.

Print version record.

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Electronic reproduction. [Place of publication not identified] : HathiTrust Digital Library, 2010. MiAaHDL

Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL