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Caloric restriction : a key to understanding and modulating aging / Edward J. Masoro.

By: Material type: TextTextSeries: Research profiles in aging ; v. 1.Publication details: Amsterdam ; Boston : Elsevier, 2002.Edition: 1st edDescription: 1 online resource (vii, 183 pages) : illustrationsContent type:
  • text
Media type:
  • computer
Carrier type:
  • online resource
ISBN:
  • 9780444511621
  • 0444511628
  • 9780080528427
  • 0080528422
Subject(s): Genre/Form: Additional physical formats: Print version:: Caloric restriction.DDC classification:
  • 612.6/7 22
LOC classification:
  • QP86 .M268 2002eb
NLM classification:
  • 2004 N-306
  • WT 116
Online resources:
Contents:
Cover -- Table of Contents -- Preface -- Chapter 1. Overview -- Chapter 2. Mortality Characteristics -- Chapter 3. Molecular and Cellular Biology -- Chapter 4. Organismic Physiology -- Chapter 5. Age-Associated Diseases -- Chapter 6. Mechanisms of the Anti-Aging Action of Caloric Restriction -- Chapter 7. Evolution of Anti-Aging Action of Caloric Restriction -- Chapter 8. Caloric Restriction Mimetics -- Index -- Last Page.
Summary: For many years, it has been known that when rats and mice are given a reduced amount of food, their life span is increased and they remain healthy and vigorous at advanced ages. What is the reason for this change in the usual pattern of aging? The evidence is overwhelming that the life extension results from a slowing of aging processes. And the factor responsible is the decrease in caloric intake. The obvious question: How does this factor work? A good question - and the reason that research on the anti-aging action of caloric restriction is today one of the most studied research areas in biological gerontology. For it is felt that if the biological mechanisms of the anti-aging action of caloric restriction can be uncovered, we would gain an understanding of the basic nature of aging processes, which would, in turn, yield possible interventions in human aging. This book aims to provide the growing number of researchers in this field (faculty, postdoctoral trainees, and graduate students) with a detailed knowledge of what is known about caloric restriction within the frame of gerontology, as well as insights on future of this field.
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For many years, it has been known that when rats and mice are given a reduced amount of food, their life span is increased and they remain healthy and vigorous at advanced ages. What is the reason for this change in the usual pattern of aging? The evidence is overwhelming that the life extension results from a slowing of aging processes. And the factor responsible is the decrease in caloric intake. The obvious question: How does this factor work? A good question - and the reason that research on the anti-aging action of caloric restriction is today one of the most studied research areas in biological gerontology. For it is felt that if the biological mechanisms of the anti-aging action of caloric restriction can be uncovered, we would gain an understanding of the basic nature of aging processes, which would, in turn, yield possible interventions in human aging. This book aims to provide the growing number of researchers in this field (faculty, postdoctoral trainees, and graduate students) with a detailed knowledge of what is known about caloric restriction within the frame of gerontology, as well as insights on future of this field.

Includes bibliographical references and index.

Cover -- Table of Contents -- Preface -- Chapter 1. Overview -- Chapter 2. Mortality Characteristics -- Chapter 3. Molecular and Cellular Biology -- Chapter 4. Organismic Physiology -- Chapter 5. Age-Associated Diseases -- Chapter 6. Mechanisms of the Anti-Aging Action of Caloric Restriction -- Chapter 7. Evolution of Anti-Aging Action of Caloric Restriction -- Chapter 8. Caloric Restriction Mimetics -- Index -- Last Page.

Print version record.

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