Recent developments in phytomedicine technology / Luis Alexandre Pedro de Freitas, Cristiane Cardoso Coreeia Teixeira and Cristina Mara Zamarioli, editors.

Online resource; title from PDF title page (EBSCO, viewed June 27, 2017)

Preface; Introduction; Chapter 1; Adulteration and Misidentification of Crude Drugs; Abstract; Introduction; Avoiding Misidentification and Adulteration of Crude Drugs Consisting of Rhizome and Root; How to Identify Bark and Wood Drugs of Renowned Value; Crude Drugs Made From Leaves and Flowers; Crude Drugs Made from Fruit; Crude Drugs Made from Seed; Glands Are Useful Structures in the Secretion of Bioactive Compounds and in Drug Identification; Conclusion; Acknowledgments; References; Chapter 2; Recent Developments in Pharmacognostic Evaluation; Abstract; Introduction

Histochemical and Classical TechniquesExtraction, Isolation and Purification of Natural Compounds; Analysis and Quantification of Secondary Metabolites in Natural Matrixes and Its Products; Gas-Chromatography and Liquid Chromatography; Hyphenated Techniques; Conclusion; References; Chapter 3; The Quality by Design (QbD) Approach to the Development of Modern Phytomedicines; Abstract; Introduction; How to Develop Phytomedicines Ensuring Internationally Harmonized Quality?; QbD Principles; QbD Development; QbD Application to Phytopharmaceuticals; Extraction; Drying; References; Chapter 4

The Importance of Experimental Design in the Standardization for Developing Analytical MethodologiesAbstract; Introduction; Location of Experimental Design within the Methodology to Develop and Standardize Analytical Methods; Analytical Target Profile (ATP); Critical Quality Attributes (CQAs); Optimization and Development Method with DOE; Method Operable Design Region (MODR); Control Strategy and Risk Assessment; AQbD Validation Method; Continuous Method Monitoring (CMM); Development of Analytical Methodologies; Brief Observations on Chromatography; Technical Terms of Chromatography

Experimental Design Applications to Standardize the Development of Analytical MethodologiesConclusion; References; Chapter 5; The Extraction of Bioactives from Plants; Abstract; Introduction; Soxhlet; Percolation; Maceration; Digestion; Dynamic Maceration; Re-Maceration; Turbo Extraction; Counter Current and Other Moving Bed Extractors; Supercritical Fluid Extraction; Microwave; Ultrassound; References; Chapter 6; Recent Developments in Drying Extracts; Abstract; Introduction; Fundamental Aspects: Drying Pharmaceutical Products; Moisture Content; Dry Bulb and Wet Bulb Temperature

Dew Point TemperatureVapor Pressure; Relative Humidity (%RH); Bound and Unbound Moisture; Water Activity; Drying Mechanism; Equilibrium Moisture Content and Sorption Isotherms; Behavior of Solids During the Drying Process; Classification of Drying Operations; Selecting Drying Equipment; Drying Equipment; Fluidized Bed Dryer; Freeze Drying; Spray Drying; Spray Congealing; Spray Freeze Dryer and Fluid Bed Atmospheric Spray Freeze Drying; Excipients for Dried Medicinal Extracts; Evaluating the Pearson and Spearman Correlations Among the Dried Extracts Characteristics; Decision-Making; References

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