TY - GEN AU - Heo,Yong-Seok AU - Heo,Yong-Seok TI - Recent Advances in Antibody Therapeutics SN - books978-3-0365-4354-3 PY - 2022/// CY - Basel PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Research & information: general KW - bicssc KW - Chemistry KW - interleukin 33 KW - ST2 receptor KW - scFv KW - C2_2E12 KW - bladder cancer KW - antibodies KW - immune checkpoint inhibitors KW - antibody-drug conjugates KW - sacituzumab govitecan KW - enfortumab vedotin KW - erdafitinib KW - cost-effectiveness KW - G protein-coupled receptor KW - membrane protein KW - antigen KW - therapeutic antibody KW - anti-angiogenesis KW - delta-like ligand KW - irinotecan KW - paclitaxel KW - VEGF KW - SARS-CoV-2 KW - spike protein KW - receptor-binding domain KW - phage display KW - monoclonal antibody KW - cytomegalovirus KW - peptide/major histocompatibility complex class I complex KW - T-cell-receptor-like antibody KW - affinity maturation KW - yeast surface display KW - combinatorial antibody library KW - agonist antibody KW - cell fate KW - bispecific antibodies KW - bioassays KW - mechanisms of action KW - binding assays KW - potency assays KW - atherosclerosis KW - inflammation KW - antibody therapy KW - blood-brain barrier KW - antibody KW - pharmacokinetics KW - disposition KW - biochemical and physicochemical properties KW - Fc binding KW - receptor-mediated transcytosis KW - brain shuttle KW - molecular Trojan horse KW - transferrin KW - anti-cancer antibody KW - antibody engineering KW - biophysical properties KW - computational methods KW - research cell bank KW - antibody therapeutics KW - recombinant antibodies KW - intracellular antibodies KW - single-chain antibody fragment KW - nanobody KW - Human papillomaviruses KW - HPV oncoproteins KW - HPV-associated cancer KW - HPV cancer therapy KW - asthma KW - refractory asthma KW - biomarker KW - n/a N1 - Open Access N2 - Since first receiving approval in 1986, antibody-based therapeutics have been the most successful modality for the treatment of various diseases. This Special Issue of IJMS, "Recent Advances in Antibody Therapeutics", presents leading-edge articles and reviews for discovery, development, and clinical applications of therapeutic antibodies, covering antibody drug conjugates (ADCs), GPCR-targeting antibodies, a functional antibody screening, bioassay of bispecific antibodies, antibody applications for cardiovascular diseases, antibody delivery to CNS, etc. The excellent studies in this Special Issue would valuable insight for scientists and clinicians in the field of therapeutic antibodies UR - https://mdpi.com/books/pdfview/book/5595 UR - https://directory.doabooks.org/handle/20.500.12854/87408 ER -