TY  - GEN
AU  - Domenicotti,Cinzia
AU  - Marengo,Barbara
AU  - Domenicotti,Cinzia
AU  - Marengo,Barbara
TI  - Paradox Role of Oxidative Stress in Cancer : State of the Art
SN  - books978-3-0365-4422-9
PY  - 2022///
CY  - Basel
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - Medicine
KW  - bicssc
KW  - Oncology
KW  - sonodynamic therapy
KW  - carbon doped titanium dioxide
KW  - sonosensitizers
KW  - ultrasound
KW  - cancer treatment
KW  - breast cancer treatment
KW  - radiotherapy
KW  - hematological malignancies
KW  - oxidative stress
KW  - lymphoma
KW  - leukemia
KW  - multiple myeloma
KW  - apoptosis
KW  - mitochondria
KW  - ultraviolet-C (UVC)
KW  - withanolide
KW  - combined treatment
KW  - oral cancer
KW  - DNA damage
KW  - cancer therapy
KW  - immune system
KW  - Hypericum perforatum
KW  - hyperforin
KW  - reactive oxygen species
KW  - pH regulation
KW  - tumor prevention
KW  - tumor therapy
KW  - cancerogenesis
KW  - inflammatory signaling
KW  - natural compounds
KW  - pancreatic cancer
KW  - antitumor agents
KW  - coordination polymers
KW  - bioinorganic chemistry
KW  - cold atmospheric plasma
KW  - reactive oxygen and nitrogen species
KW  - nitrite
KW  - cancer stem cells
KW  - chemoresistance
KW  - glutathione
KW  - lipid peroxidation
KW  - ZEB-1
KW  - GPX4
KW  - ferroptosis
KW  - HO-1
KW  - Nrf2
KW  - cancer progression
KW  - patients
KW  - therapy
KW  - prognosis
KW  - biomarker
KW  - Eprenetapopt
KW  - Erastin
KW  - glutathione (GSH)
KW  - SLC7A11
KW  - iron
KW  - NRF2
KW  - n/a
N1  - Open Access
N2  - Reactive oxygen species (ROS) are produced by healthy cells and are maintained at physiological levels by antioxidant systems. However, when ROS increase in number, a condition of oxidative stress occurs, leading to many human diseases, including cancer. The relationship between oxidative stress and cancer is complex since ROS play a double-edged role in cancer development and under therapy response. This paradox represents a great challenge for researchers and needs to be investigated. The articles collected in this Special Issue can help to clarify the role of ROS modulation in cancer prevention and treatment, and to dissect the molecular mechanisms underlying its paradoxical role in order to counteract carcinogenesis or enhance sensitivity to anticancer therapy
UR  - https://mdpi.com/books/pdfview/book/5665
UR  - https://directory.doabooks.org/handle/20.500.12854/87477
ER  -