TY  - GEN
AU  - Bodis,Stephan
AU  - Ghadjar,Pirus
AU  - Van Rhoon,Gerard C.
AU  - Bodis,Stephan
AU  - Ghadjar,Pirus
AU  - Van Rhoon,Gerard C.
TI  - Oncologic Thermoradiotherapy: Need for Evidence, Harmonisation, and Innovation
SN  - books978-3-0365-4531-8
PY  - 2022///
CY  - Basel
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - Medicine
KW  - bicssc
KW  - Oncology
KW  - perfusion estimation
KW  - temperature monitoring
KW  - conductivity reconstruction
KW  - systems medicine
KW  - immune system in silico
KW  - perceptron
KW  - antigen pattern
KW  - danger signal
KW  - fractionation
KW  - immune response
KW  - head and neck cancer
KW  - hyperthermia
KW  - reirradiation
KW  - treatment outcome
KW  - hyperthermia treatment planning
KW  - adaptive planning
KW  - temperature optimization
KW  - low-middle-income group countries
KW  - cancer
KW  - radiotherapy
KW  - chemotherapy
KW  - recurrent breast cancers
KW  - cervical cancer
KW  - head and neck cancers
KW  - cost-effective
KW  - meta-analysis
KW  - intensity-modulated radiotherapy
KW  - prostate cancer
KW  - thermal dose
KW  - thermometric parameters
KW  - preclinical data
KW  - clinical evidence
KW  - modulated electro-hyperthermia
KW  - abscopal effect
KW  - locally advanced cervical cancer
KW  - resource-constrained setting
KW  - radiosensitiser
KW  - rectal cancer
KW  - chemoradiotherapy
KW  - tumour control
KW  - loco-regional hyperthermia
KW  - oncology
KW  - cellular selection
KW  - bioelectromagnetics
KW  - complexity
KW  - immune-effects
KW  - moderate hyperthermia
KW  - deep hyperthermia
KW  - radiative hyperthermia
KW  - patterns of care
KW  - reimbursement
KW  - regional hyperthermia
KW  - neoadjuvant chemoradiation
KW  - survival
KW  - induced
KW  - brachytherapy
KW  - prostatic neoplasms
KW  - interstitial hyperthermia
KW  - treatment plan optimization
KW  - prostate
KW  - thermoradiotherapy
KW  - linear quadratic model
KW  - biological modeling
KW  - thermal dosimetry
KW  - hypoxia
KW  - radiation therapy
KW  - reoxygenation
KW  - perfusion
KW  - oxygen consumption rate
KW  - local tumor control
KW  - biomarker
KW  - immune phenotype
KW  - hyperthermia treatment sequence
KW  - breast cancer
KW  - immune checkpoint molecules
KW  - dendritic cell activation
KW  - n/a
N1  - Open Access
N2  - The road of acceptance of oncologic thermotherapy/hyperthermia as a synergistic modality in combination with standard oncologic therapies is still bumpy. This is partially due to the lack of level I evidence from international, multicentric, randomized clinical trials including large patient numbers and a long term follow-up. Therefore we need more level I EVIDENCE from clinical trials, we need HARMONISATION and global acceptance for existing technologies and a common language understood by all stakeholders and we need INNOVATION in the fields of biology, clinics and technology to move thermotherapy/hyperthermia forward. This is the main focus of this reprint. In this reprintyou find carefully selected and peer-reviewed contributions from Africa, America, Asia, and Europe. The published papers from leading scientists from all over the world covering a broad range of timely research topics might also help to strengthen thermotherapy on a global level
UR  - https://mdpi.com/books/pdfview/book/5714
UR  - https://directory.doabooks.org/handle/20.500.12854/87516
ER  -