TY - GEN AU - Ferraris,Davide Maria AU - Miggiano,Riccardo AU - Rizzi,Menico AU - Ferraris,Davide Maria AU - Miggiano,Riccardo AU - Rizzi,Menico TI - Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment SN - books978-3-03936-659-0 PY - 2020/// CY - Basel, Switzerland PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Research & information: general KW - bicssc KW - Biology, life sciences KW - Mycobacterium tuberculosis KW - line probe assay KW - second-line drugs KW - drug resistance KW - XDR-TB KW - MDR-TB KW - omics analysis KW - TB treatment KW - system analysis KW - Beijing B0/W148 KW - Mycobacterium smegmatis KW - imidazo[1,2-b][1,2,4,5]tetrazine KW - MmpS5-MmpL5 KW - efflux KW - drug discovery KW - tuberculosis KW - immune activation KW - HLA-DR KW - CD38 KW - treatment response KW - Mycobacterium KW - macrophage KW - apoptosis KW - effector KW - cytokine KW - microRNA KW - Beijing genotype KW - Central Asia Outbreak KW - murine infection model KW - Virulence KW - pre-XDR-TB KW - Mycobacterium avium KW - unique metabolic pathways KW - subtractive genomics KW - drug target KW - uncharacterized proteins KW - BM-MSCs KW - Mtb KW - bone-homing KW - stem cell niche KW - latent tuberculosis KW - relapse KW - liposomes KW - M. tuberculosis KW - host-pathogen interactions KW - immune response KW - antitubercular drug discovery KW - antitubercular treatments KW - IL-18 KW - IL-18BP KW - IL-18R KW - gene expression N1 - Open Access N2 - Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Health Organization (WHO), TB is considered the ninth cause of death worldwide and the leading cause of mortality by a single infectious agent, with the highest rate of infections and death toll rate mostly concentrated in developing and low-income countries. We present here the editorial section to the Special Issue entitled "Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment" that includes 7 research articles and a review. The scientific contributions included in the Special Issue mainly focus on the characterization of MTB strains emerging in TB endemic countries as well as on multiple mechanisms adopted by the bacteria to resist and to adapt to antitubercular therapies UR - https://mdpi.com/books/pdfview/book/2925 UR - https://directory.doabooks.org/handle/20.500.12854/69153 ER -