TY  - GEN
AU  - Pellicano,Rinaldo
AU  - Fagoonee,Sharmila
AU  - Pellicano,Rinaldo
AU  - Fagoonee,Sharmila
TI  - 3Ts in Gastrointestinal Microbiome Era: Technology, Translational Research and Transplant
SN  - books978-3-0365-2797-0
PY  - 2021///
CY  - Basel, Switzerland
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - Public health & preventive medicine
KW  - bicssc
KW  - Bacteroides ovatus
KW  - Bifidobacterium adolescentis
KW  - Dysbiosis
KW  - Faecalibacterium prausnitzii
KW  - Ruminococcus gnavus
KW  - type 1 diabetes
KW  - microbiota
KW  - microbiome
KW  - auto-immunity
KW  - gut permeability
KW  - gut
KW  - IBS
KW  - celiac disease
KW  - enteropathy
KW  - gluten
KW  - therapy
KW  - gut microbiota
KW  - precision medicine
KW  - Clostridium difficile
KW  - inflammatory bowel disease
KW  - ulcerative colitis
KW  - irritable bowel disease
KW  - metabolic syndrome
KW  - gastric microbiota
KW  - transient
KW  - persistent
KW  - culture
KW  - sequencing
KW  - Helicobacter pylori
KW  - fecal microbiota transplantation
KW  - feces donor
KW  - fecal microbiota
KW  - flow cytometry
KW  - viability of bacteria
KW  - next-generation sequencing
KW  - culturing of fecal microbiota
KW  - Alzheimer's disease
KW  - microbiota-gut-brain axis
KW  - neurodegenerative disease
KW  - intestinal flora
KW  - necrotizing enterocolitis
KW  - intestinal microbiology
KW  - infant gut
KW  - metabolomics
KW  - IL-6
KW  - IL-8
KW  - IL-12p70
KW  - intestinal permeability
KW  - zonulin
KW  - gut virome
KW  - steatosis
KW  - cirrhosis
KW  - hepatocellular carcinoma
KW  - gastrointestinal
KW  - technology
KW  - high-throughput
KW  - crohn's disease
KW  - mononuclear cells
KW  - transient receptor potential channel
KW  - pancreatic diseases
KW  - acute pancreatitis
KW  - chronic pancreatitis
KW  - diabetes mellitus
KW  - pancreatic ductal adenocarcinoma
KW  - pancreatic cystic neoplasms
N1  - Open Access
N2  - We have entered a new era where some concepts of the complex community of microorganisms (microbiota comprising bacteria, fungi, viruses, bacteriophages and helminths) are being re-discovered and re-visited. Microbiota and human interaction is not new; they have shared a long history of co-existence. Nevertheless, the opportunities to understand the role of these microorganisms in human diseases and to design a potential treatment were limited. At present, thanks to development of innovative and cutting-edge molecular biological and microbiological technologies as well as clinical informatics and bioinformatics skills, microbiome application is moving into clinics. Approaches to therapy based on prebiotics, probiotics and lately on fecal microbiota transplantation has revolutionized medicine. Microbiota outnumbers our genes and is now regarded as another organ of the body. The gastrointestinal tract and gut microbiota display a well-documented symbiotic relationship. Disruption of intestinal microbiota homeostasis-called dysbiosis-has been associated with several diseases. Whether dysbiosis is a cause or consequence of disease initiation and progression still needs to be investigated in more depth. The aim of this book is to highlight recent advances in the field of microbiome research, which are now shaping medicine, and current approaches to microbiome-oriented therapy for gastrointestinal diseases.                                                                                                                                    Dr. Rinaldo Pellicano                                                                                                                           Dr. Sharmila Fagoonee                                                                                                                  Guest Editors
UR  - https://mdpi.com/books/pdfview/book/4793
UR  - https://directory.doabooks.org/handle/20.500.12854/76262
ER  -