TY - GEN AU - Khutoryanskiy,Vitaliy AU - Al-Obaidi,Hisham AU - Khutoryanskiy,Vitaliy AU - Al-Obaidi,Hisham TI - Solid Dispersions for Drug Delivery : Applications and Preparation Methods SN - books978-3-0365-2638-6 PY - 2022/// CY - Basel PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Medicine KW - bicssc KW - Pharmaceutical industries KW - solid dispersions KW - drug delivery KW - biological applications KW - solid dispersion KW - delivery system KW - polymeric carriers KW - antichagasic activity KW - fexofenadine hydrochloride KW - PEG 20,000 KW - poloxamer188 KW - dissolution KW - absorption KW - green nanotechnology KW - raloxifene KW - nanoemulsion KW - core-sheath nanofibers KW - response surface methodology KW - ex vivo drug permeation KW - in vivo pharmacokinetic studies KW - acalabrutinib KW - amorphous solid dispersion KW - acid-reducing agent KW - bioavailability enhancement KW - kinase inhibitor KW - pH effect KW - proton pump inhibitor KW - spray drying KW - hydrogen bonding KW - hydrophobicity KW - poly(N-vinyl pyrrolidone) KW - poly(2-oxazolines) KW - crystallinity KW - hydrophobic drug KW - amorphous KW - ibuprofen KW - drug-rich phase KW - liquid-liquid phase separation KW - permeability enhancement KW - cocrystals KW - coamorphous KW - solubility KW - dry powder inhalers KW - pulmonary drug delivery KW - acid reducing agent KW - in silico prediction KW - absorption modeling KW - GastroPlus KW - paroxetine KW - nanosuspension KW - oral fast dissolving film KW - factorial design KW - rapid release KW - ex vivo permeation KW - bioavailability KW - n/a N1 - Open Access N2 - Since their first application in the improvement of solubility of orally delivered drugs, applications of solid dispersions have considerably expanded to include cancer, infections, and inflammatory conditions. This book presents recent advancements in the development and use of solid dispersions for different therapeutic applications. This book can be particularly useful for researchers as well as postgraduate students in formulation sciences and drug delivery. Undergraduate students will also find elements of this book very relevant to scientific fundamentals such as solubility and crystallization of amorphous materials as well as drug delivery challenges UR - https://mdpi.com/books/pdfview/book/4817 UR - https://directory.doabooks.org/handle/20.500.12854/78726 ER -