TY  - GEN
AU  - Jae Young Seong
AU  - Hubert Vaudry
TI  - Neuropeptide GPCRs in Neuroendocrinology
SN  - 978-2-88919-267-0
PY  - 2014///
PB  - Frontiers Media SA
KW  - Transduction pathways
KW  - G protein-coupled receptors
KW  - Neuroendocrinology
KW  - Heptahelical receptors
KW  - Neuropeptides
KW  - Signaling mechanisms
KW  - Biologically active peptides
KW  - seven-transmembrane domain receptors
N1  - Open Access
N2  - The human genome encompasses ~ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. GPCRs are also major drug targets and hence possess a strong potential for the development of innovative pharmaceuticals. The aim of this Research Topic was to assemble a series of review articles and original research papers on neuropeptide GPCRs and their ligands that would illustrate the different facets of the studies currently conducted in this domain
UR  - http://journal.frontiersin.org/researchtopic/848/neuropeptide-gpcrs-in-neuroendocrinology
UR  - https://directory.doabooks.org/handle/20.500.12854/54523
ER  -