TY  - GEN
AU  - Laganà,Antonio Simone
AU  - La Rosa,Valentina Lucia
AU  - Laganà,Antonio Simone
AU  - La Rosa,Valentina Lucia
TI  - Endometriosis Research : From Bench to Bedside
SN  - books978-3-0365-2798-7
PY  - 2022///
CY  - Basel
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - Medicine
KW  - bicssc
KW  - BTG1
KW  - endometriosis
KW  - human endometrial stromal cells
KW  - endometrium
KW  - uterus
KW  - purinergic signaling
KW  - ATP
KW  - pathogenesis
KW  - genetics
KW  - epigenetics
KW  - immunology
KW  - ion channels
KW  - etiology
KW  - CFTR
KW  - aquaporin
KW  - chloride channels
KW  - biomarker
KW  - angiogenesis
KW  - cytokines
KW  - urinary biomarkers
KW  - genetic polymorphisms
KW  - SNPs
KW  - aetiology
KW  - Mediterranean population
KW  - Sardinian population
KW  - peritoneal fluid
KW  - microenvironment
KW  - precision medicine
N1  - Open Access
N2  - Endometriosis is defined as the presence of endometrial-like endometrial cells, glands, and stroma outside the uterus, causing a strong inflammatory-like microenvironment in the affected tissue. The exact prevalence of endometriosis is unknown, but estimates range from 2%-10% of women of reproductive age, to 50% of infertile women. Its etiopathogenesis of endometriosis still remains controversial-immune, hormonal, genetic, and epigenetic factors may be all involved, and several theories have been proposed to explain it.This book aims to summarize recent ground-breaking studies that may open new scenarios and change the perspective of the topic, including cutting-edge elements about diagnosis, pharmacologic and surgical treatments, as well as basic/translational science (immunology, cell biology, genetics, and epigenetics) pieces of evidence, to unravel new pathways to follow for the future diagnosis and management of endometriosis, and to improve our current knowledge of its aetiology
UR  - https://mdpi.com/books/pdfview/book/4895
UR  - https://directory.doabooks.org/handle/20.500.12854/78800
ER  -