TY  - GEN
AU  - Daniels,Rolf
AU  - Lunter,Dominique
AU  - Daniels,Rolf
AU  - Lunter,Dominique
TI  - Semisolid Dosage
SN  - books978-3-03936-949-2
PY  - 2020///
CY  - Basel, Switzerland
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - Medicine
KW  - bicssc
KW  - dermal drug delivery
KW  - diffusion cell
KW  - Franz diffusion
KW  - Skin-PAMPA
KW  - Strat-M® membrane
KW  - nanocarrier
KW  - nonivamide
KW  - methyl cellulose
KW  - skin penetration
KW  - substantivity
KW  - thermogel
KW  - tacrolimus formulation
KW  - nanogels
KW  - drug delivery
KW  - human excised skin
KW  - Jurkat cells
KW  - in situ hydrogel-forming powder
KW  - nitric oxide-releasing formulation
KW  - S-nitrosoglutathione (GSNO)
KW  - antibacterial
KW  - wound dressing
KW  - wound healing
KW  - dermal delivery
KW  - porcine skin
KW  - in vitro permeation
KW  - methadone
KW  - pain
KW  - in vitro
KW  - permeation
KW  - niacinamide
KW  - solvent
KW  - PAMPA
KW  - skin
KW  - curcumin
KW  - deformable liposomes
KW  - liposome surface charge
KW  - hydrogel
KW  - chitosan
KW  - wound therapy
KW  - IVRT
KW  - metronidazole
KW  - topical cream
KW  - semisolid dosage forms
KW  - sameness
KW  - FDA's SUPAC-SS guidance
KW  - acceptance criteria
KW  - positive and negative controls
KW  - discriminatory ability
KW  - Amphotericin B
KW  - Sepigel 305®
KW  - Leishmania infantum
KW  - cutaneous leishmaniasis
KW  - topical treatment
KW  - birch bark extract
KW  - oleogels
KW  - hydrogen bonding
KW  - triterpene
KW  - rheology
KW  - gel strength
KW  - eosinophilic esophagitis
KW  - budesonide
KW  - xanthan gum
KW  - guar gum
KW  - mucoadhesion
KW  - esophagus permeability
KW  - rheological characterization
KW  - pediatric medicine
KW  - compounded preparation
KW  - non-ionic emulsifiers
KW  - intercellular lipids
KW  - confocal Raman spectroscopy (CRS)
KW  - polyethylene glycol alkyl ethers
KW  - polyethylene glycol sorbitan fatty acid esters
KW  - n/a
N1  - Open Access
N2  - Even in ancient times, semi-solid preparations for cutaneous application, popularly known as ointments, played an important role in human society. An advanced scientific investigation of "ointments" as dosage forms was initiated in the 1950s. It was only from then on that the intensive physico-chemical characterization of ointments as well as the inclusion of dermatological aspects led to a comprehensive understanding of the various interactions between the vehicle, the active ingredient and the skin. From then on, many researchers were involved in optimizing semi-solid formulations with respect to continuously changing therapeutic and patient needs. Aspects that have been dealt with were the optimization of dermato-biopharmaceutical properties and many different issues related to patient compliance, such as skin tolerance, applicability, and cosmetic appeal. Moreover, processing technology has been improved and analytical techniques were developed and refined in order to enable the improved characterization of the formulation itself as well as its interaction with the skin. This Special Issue serves to highlight and capture the contemporary progress and current research on semi-solid formulations as dermal drug delivery systems. We invite articles on all aspects of semi-solid formulations, highlighting the research currently undertaken to improve and better understand these complex drug delivery systems with respect to their formulation, processing and characterization issues
UR  - https://mdpi.com/books/pdfview/book/2753
UR  - https://directory.doabooks.org/handle/20.500.12854/68985
ER  -