TY  - GEN
AU  - Lee,Nikki
AU  - Yee,Nelson
TI  - Cancer Biomarkers and Targets in Digestive Organs
SN  - books978-3-03921-464-8
PY  - 2019///
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - n/a
KW  - liver graft injury
KW  - HFE
KW  - neurokinin
KW  - chemotherapy
KW  - intestinal tumors
KW  - therapeutic targets
KW  - biliary tract carcinoma
KW  - hepatocellular carcinoma
KW  - clinical trial
KW  - cell adhesion molecules
KW  - colorectal cancer
KW  - biomarkers
KW  - phenotypic mosaics
KW  - gastrointestinal oncology
KW  - Asian Cancer Research Group (ACRG)
KW  - biomarker
KW  - psychosocial support
KW  - precision therapy
KW  - pancreatic carcinoma
KW  - precision medicine
KW  - Liver transplantation
KW  - predictive biomarkers
KW  - CD274
KW  - cholecystokinin
KW  - The Cancer Genome Atlas (TCGA)
KW  - gastrin
KW  - pembrolizumab
KW  - immunotherapy
KW  - gastrin-releasing peptide
KW  - stereotactic body radiation therapy
KW  - immunohistochemistry
KW  - gastric carcinoma
KW  - liver transplant
KW  - CAM invasion assay
KW  - intragraft gene expression profiles
KW  - molecular profiling
KW  - targeted therapy
KW  - neurotensin
KW  - intestinal disorder
KW  - ramucirumab
KW  - next-generation sequencing
KW  - colorectal carcinoma
KW  - tumor progenitor
KW  - circulating tumor cells
KW  - gastrointestinal malignancies
KW  - bombesin
KW  - trastuzumab
KW  - somatostatin
KW  - zebrafish
KW  - G protein-coupled receptors
N1  - Open Access
N2  - Identification and development of cancer biomarkers and targets have greatly accelerated progress towards precision medicine in oncology. Studies of tumor biology have not only provided insights into the mechanisms underlying carcinogenesis, but also led to discovery of molecules that have been developed into cancer biomarkers and targets. Multi-platforms for molecular characterization of tumors using next-generation genomic sequencing, immunohistochemistry, in situ hybridization, and blood-based biopsies have greatly expanded the portfolio of potential biomarkers and targets. These cancer biomarkers have been developed for diagnosis, early detection, prognosis, and prediction of treatment response. The molecular targets have been exploited for anti-cancer therapy and delivery of therapeutic agents. This Special Issue of Biomedicines focuses on recent advances in the discovery, characterization, translation, and clinical application of cancer biomarkers and targets in malignant diseases of the digestive system. The goal is to stimulate basic and translational research and clinical collaboration in this exciting field with the hope of developing strategies for prevention and early detection/diagnosis of cancer in digestive organs, and improving therapeutic and psychosocial outcomes in patients with these malignant diseases
UR  - https://mdpi.com/books/pdfview/book/1534
UR  - https://directory.doabooks.org/handle/20.500.12854/42637
ER  -