TY  - GEN
AU  - Oswald,Isabelle P.
AU  - Pinton,Philippe
AU  - Alassane-Kpembi,Imourana
TI  - Effects of Mycotoxins on the Intestine
SN  - books978-3-03897-783-4
PY  - 2019///
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - toxicity
KW  - intestinal epithelial cells
KW  - n/a
KW  - piglets
KW  - toll-like receptors
KW  - permeability
KW  - aflatoxin M1
KW  - pig
KW  - N-acetylcysteine
KW  - pigs
KW  - histology
KW  - pre-pubertal gilts
KW  - histopathological lesions
KW  - Mitochondrial apoptosis
KW  - explant technique
KW  - Lactobacillus
KW  - liver
KW  - ergot alkaloids
KW  - digestive tract
KW  - ultrastructure
KW  - hydrogen-rich water
KW  - genotoxicity
KW  - proliferating cell nuclear antigen
KW  - mycotoxin
KW  - feed
KW  - intestinal morphology
KW  - functional oligosaccharides
KW  - Saccharomyces cerevisiae boulardii CNCM I-1079
KW  - jejunum
KW  - small intestine
KW  - detoxification
KW  - vasoactive intestinal polypeptide
KW  - PCR
KW  - atlantic salmon
KW  - ileum
KW  - microbiota
KW  - sclerotia
KW  - zearalenone
KW  - intestine
KW  - doses
KW  - mycotoxins
KW  - transcriptome
KW  - lipid metabolism
KW  - Zearalenone
KW  - caecal water
KW  - mice
KW  - deoxynivalenol
KW  - aflatoxin B1
KW  - goblet cells
KW  - inflammation
KW  - intestinal bacterial flora
KW  - SIEC02 cells
KW  - piglet
KW  - colon microbiota
KW  - tight junctions
KW  - tight junction
KW  - suppressor of cytokine signaling
KW  - ochratoxin A
KW  - Claviceps
KW  - T-2 toxin
KW  - MiSeq 16S rDNA sequencing
KW  - lactulose
KW  - Clostridium sp. WJ06
KW  - swine
KW  - intestinal microbiota
KW  - fumonisin
KW  - response
KW  - contaminated feed
KW  - Fusarium mycotoxins
KW  - microbial diversity
KW  - enteric nervous system
KW  - large intestine
KW  - ultrastructural changes
KW  - oxidative stress
N1  - Open Access
N2  - Mycotoxins are secondary metabolites produced by several fungal species. They can contaminate human food and animal feed, and have been a threat for thousands of years. The gastrointestinal tract is the first target when ingesting mycotoxin-contaminated food or feed. As unlikely as it sounds, the investigations concerning the effects of mycotoxins on the intestine are still in their early stages. This book gathers the most recent advances related to the characterization of the intestinal toxicity of mycotoxins. Substantial data assembled on the damage caused to a number of histological structures and functions of the intestine remove any remaining doubt about this organ being a primary target for the toxicity of mycotoxins. An interesting overview of the detrimental effects of mycotoxins on the gut-hosted microbiota—now regarded as a fully-fledged organ associated with the gut—is also given. Finally, outstanding contributions in this book address questions relating to the suitability of current regulations to protect against alterations of the intestine, and to the efficacy assessment of new detoxification strategies using the intestinal toxicity of mycotoxins as a relevant endpoint
UR  - https://mdpi.com/books/pdfview/book/1275
UR  - https://directory.doabooks.org/handle/20.500.12854/45892
ER  -