TY  - GEN
AU  - Devkota,Hari Prasad
AU  - Devkota,Hari Prasad
TI  - Plant-Based Bioactive Natural Products: Insights into Molecular Mechanisms of Action
SN  - books978-3-0365-2413-9
PY  - 2021///
CY  - Basel, Switzerland
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - Medicine
KW  - bicssc
KW  - foodborne diseases
KW  - giardiasis
KW  - herbal drugs
KW  - ethnobotany
KW  - toxoplasmosis
KW  - srophularia buergeriana
KW  - cognitive impairment
KW  - amyloid beta
KW  - tau phosphorylation
KW  - oxidative stress
KW  - anti-apoptotic
KW  - Terminalia chebula fruit
KW  - osteoarthritis
KW  - AyuFlex®
KW  - cartilage collapse
KW  - MMPs
KW  - inflammation response
KW  - vascular inflammation
KW  - liensinine
KW  - VSMC
KW  - macrophage
KW  - proliferation
KW  - migration
KW  - Nigella sativa
KW  - methicillin-resistant
KW  - Staphylococcus aureus
KW  - synergism
KW  - beta-lactam
KW  - antibiotics
KW  - artichoke by-products
KW  - phenolic compounds
KW  - HPLC-ESI-TOF-MS
KW  - PLE
KW  - GRAS
KW  - Scrophularia buergeriana
KW  - anti-amnesic effect
KW  - cholinergic neurotransmission
KW  - anti-oxidant
KW  - anti-inflammation
KW  - Vepris macropylla
KW  - essential oil
KW  - citral
KW  - antiproliferative activity
KW  - fluorescence and scanning electron microscopy
KW  - human breast cancer cell line
KW  - Vaccinium species
KW  - phytochemicals
KW  - berry
KW  - leaf
KW  - anti-inflammatory pathways
KW  - endothelial dysfunction
KW  - natural products
KW  - bioactive compounds
KW  - medicinal plants
KW  - bioactivity
KW  - mechanism of action
KW  - traditional medicines
N1  - Open Access
N2  - Medicinal plants have been used for the maintenance of human health since ancient times, in the form of food, spices, and traditional medicines. Medicinal plant-based traditional medicines serve as the primary healthcare systems in various countries even in recent times. Alongside this, medicinal plants have also served as the one of the main sources for the discovery of new therapeutic agents. At present, various plant extracts and their isolated phytochemicals are screened and evaluated for their diverse pharmacological activities related to both communicable and non-communicable diseases. However, comparatively little focus is given to the detailed mechanism of action of these agents on the molecular level. Molecular mechanism-based studies are essential for the development of evidence-based traditional medicines as well as for the development of isolated natural products as the lead candidates for novel drug discovery.   This main focus of this Special Issue "Plant-based Bioactive Natural Products: Insights into Molecular Mechanisms of Action" is to cover the recent advances in science related to the molecular mechanisms of action of natural products. A total of nine articles were published in this Special Issue, including two original research articles and two review articles.   This Special Issue has provided some new experimental data on bioactive natural products and their detailed mechanisms of action for biological activities. Similarly, review articles have provided state-of-the-art information on the related topics. I would like to thank all the authors for submitting their manuscripts and the reviewers and editors for their contribution to this Special Issue. Furthermore, I am also grateful to the handling editors and staffs of Applied Sciences for their support during the preparation and finalization of this Special Issue
UR  - https://mdpi.com/books/pdfview/book/4562
UR  - https://directory.doabooks.org/handle/20.500.12854/76970
ER  -