TY - GEN AU - Caltabiano,Rosario AU - Loreto,Carla AU - Caltabiano,Rosario AU - Loreto,Carla TI - Immunohistochemical Expression SN - books978-3-0365-0401-8 PY - 2021/// CY - Basel, Switzerland PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Medicine KW - bicssc KW - training exercise KW - NGAL KW - VDR KW - kidney KW - heart KW - immunohistochemistry KW - ABCB5 KW - uveal melanoma KW - prognosis KW - metastasis KW - pericardium KW - cytokeratin KW - c-kit KW - PDGFR KW - initial lymphatics KW - macroH2A KW - prognostic factor KW - SLC22A12 KW - URAT1 KW - hypouricemia KW - uric acid transporters KW - excretion fraction of uric acid KW - Hsp27 KW - Hsp60 KW - Hsp70 KW - Hsp90 KW - molecular chaperone KW - chaperonopathies KW - thyroid KW - follicular adenoma KW - follicular carcinoma KW - differential diagnosis KW - carcinogenesis KW - matrix metalloproteinases KW - temporomandibular joint disorder KW - temporomandibular joint KW - DEN KW - liver KW - inflammation KW - ultra-structural changes KW - oxidative stress KW - EGCG KW - Vitamin D KW - prostate cancer KW - urinary tract malformations KW - megacystis KW - enteric nervous system KW - outcome and prognosis KW - WT1 KW - human embryonal/fetal tissues KW - neoplastic tissue KW - n/a N1 - Open Access N2 - Immunohistochemistry (IHC) is an ancillary method, widely used in pathologists' practice, that allows identifying diagnostic and prognostic/predictive of therapeutic response protein markers on tissue samples by the use of specific monoclonal antibodies and chromogenic substances that guarantee the visualization of an antibody-antigene binding complex under a light microscope [1]. Coon et al., in 1941 [2], first introduced the use of fluorochrome-conjugated antibodies in clinical practice. Since then, IHC has gone from being a useful tool for identifying the differentiation line of otherwise undifferentiated cells to a technique capable of providing not only diagnostic but also prognostic and predictive indications of responses to specific therapeutic options [1,3]. The abovementioned peculiarities have made IHC one of the most used ancillary methods in the histopathological approach to human neoplastic and non-neoplastic diseases [3-5]. This Special Issue contains 11 accepted papers that provide readers with a comprehensive update on current and future applications of IHC in medical practice UR - https://mdpi.com/books/pdfview/book/3867 UR - https://directory.doabooks.org/handle/20.500.12854/76432 ER -