TY  - GEN
AU  - Gouw,Arvin M.
AU  - Jaishankar,Amritha
AU  - Brooks,George A.
AU  - Gouw,Arvin M.
AU  - Jaishankar,Amritha
AU  - Brooks,George A.
TI  - Applying Next Generation Sequencing and Transgenic Models to Rare Disease Research
SN  - 978-2-88963-524-5
PY  - 2020///
PB  - Frontiers Media SA
KW  - Science: general issues
KW  - bicssc
KW  - Medical genetics
KW  - Rare disease
KW  - Genomics
KW  - Next generation sequencing
KW  - transgenic
KW  - genetic analysis
N1  - Open Access
N2  - A rare disease is a disease that occurs infrequently in the general population, typically affecting fewer than 200,000 Americans at any given time. More than 30 million people in the United States of America (USA) and 350 million people globally suffer from rare diseases. Out of the 7000+ known rare diseases, less than 5% have approved treatments. Rare diseases are frequently chronic, progressive, degenerative, and life-threatening, compromising the lives of patients by loss of autonomy. In the USA, it can take years for a rare disease patient to receive a correct diagnosis. The socioeconomic burden for rare disease is huge. For those living with diagnosed rare diseases, there is no support system or resource bank for navigating financial, educational, or other aspects of having a rare disease. The purpose of this Research Topic is to bring together leading researchers, non-profit organizations, healthcare providers/diagnostic companies, and pharma/biotech/CROs in the field to provide a broad perspective on the latest advances, challenges, and opportunities in rare disease research
UR  - https://www.frontiersin.org/research-topics/5679/applying-next-generation-sequencing-and-transgenic-models-to-rare-disease-research#overview
UR  - https://directory.doabooks.org/handle/20.500.12854/73676
ER  -