TY - GEN AU - Hitzmann,Bernd AU - Hitzmann,Bernd TI - Bioprocess Monitoring and Control SN - books978-3-03936-933-1 PY - 2020/// CY - Basel, Switzerland PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Research & information: general KW - bicssc KW - Biology, life sciences KW - bioenvironmental control KW - model-predictive controller KW - zonal controlling KW - dynamic modelling KW - flotation KW - bioleaching KW - frother KW - mixed culture KW - machine learning KW - Raman spectroscopy KW - downstream processing KW - chromatography KW - flow cell KW - extended Kalman filter KW - biotechnological processes KW - bioreactor control KW - specific growth rate control KW - batch-to-batch reproducibility KW - thermal sensation KW - thermal comfort KW - machine-learning KW - prediction KW - adaptive controlling KW - thermal growth curve KW - temperature modeling KW - thermoregulation KW - monitoring and control KW - bioprocess engineering KW - calorimetry KW - biocontrol agent KW - Bacillus subtilis natto KW - isolation KW - molecular identification KW - medium optimization KW - antimicrobial activity KW - bactericides KW - spectral analyses KW - biological selenate reduction KW - electron donor competition KW - nitrate KW - perchlorate KW - sequencing batch KW - Pseudomonas KW - siderophores KW - antagonism KW - batch fermentation KW - exponential fed-batch fermentation KW - bio-friendly formulations KW - biocontrol KW - nonlinear state estimation KW - geometric observer KW - bioreactor KW - continuous system KW - model-based sensor KW - well-defined macromolecules KW - sequence-defined macromolecules KW - sequence-defined polymers KW - conjugated oligomers KW - oligo(arylene ethynylene)s KW - biosensors KW - sensors KW - process monitoring KW - bioprocess monitoring and control KW - signal noise management KW - dielectric spectroscopy KW - PAT KW - microbial bioprocessing KW - n/a N1 - Open Access N2 - Process monitoring and control are fundamental to all processes; this holds especially for bioprocesses, due to their complex nature. Usually, bioprocesses deal with living cells, which have their own regulatory systems. It helps to adjust the cell to its environmental condition. This must not be the optimal condition that the cell needs to produce whatever is desired. Therefore, a close monitoring of the cell and its environment is essential to provide optimal conditions for production. Without measurement, no information of the current process state is obtained. In this book, methods and techniques are provided for the monitoring and control of bioprocesses. From new developments for sensors, the application of spectroscopy and modelling approaches, the estimation and observer implementation for ethanol production and the development and scale-up of various bioprocesses and their closed loop control information are presented. The processes discussed here are very diverse. The major applications are cultivation processes, where microorganisms were grown, but also an incubation process of bird's eggs, as well as an indoor climate control for humans, will be discussed. Altogether, in 12 chapters, nine original research papers and three reviews are presented UR - https://mdpi.com/books/pdfview/book/2827 UR - https://directory.doabooks.org/handle/20.500.12854/69058 ER -