TY  - GEN
AU  - Pereira,Maria Carmo
AU  - Loureiro,Joana
AU  - Pereira,Maria Carmo
AU  - Loureiro,Joana
TI  - PLGA Based Drug Carrier and Pharmaceutical Applications
SN  - books978-3-0365-0221-2
PY  - 2021///
CY  - Basel, Switzerland
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - Medicine
KW  - bicssc
KW  - PLGA
KW  - nanoscaled drug delivery
KW  - LED
KW  - cancer
KW  - serum stability
KW  - reactive oxygen species
KW  - cellular uptake
KW  - terahertz spectroscopy
KW  - microspheres
KW  - drug delivery
KW  - formulation development
KW  - molecular mobility
KW  - vitamin E
KW  - tocopherol
KW  - PLA
KW  - core-shell nanoparticles
KW  - controlled drug release
KW  - BMP-2
KW  - PLGA nanoparticles
KW  - Pluronic F68
KW  - oxaliplatin
KW  - hydrogel
KW  - intra-abdominal anti-adhesion barrier
KW  - colorectal cancer
KW  - experimental design
KW  - fractional factorial design
KW  - O6-methylguanine DNA methyltransferase (MGMT) protein
KW  - glioblastoma multiforme
KW  - smart nanocarriers
KW  - folic acid
KW  - verteporfin
KW  - cisplatin
KW  - SKOV-3 cells
KW  - CHO-K1 cells
KW  - electroporation
KW  - theranostic cargo
KW  - double emulsion approach
KW  - NSAIDs
KW  - polymeric film
KW  - topical drug delivery
KW  - trolamine salicylate
KW  - triamcinolone acetonide
KW  - microcrystal
KW  - PLGA microsphere
KW  - local delivery
KW  - spray-drying technique
KW  - intra-articular injection
KW  - joint retention
KW  - systemic exposure
KW  - gadolinium
KW  - drug release
KW  - polymeric nanocarrier
KW  - sorafenib
KW  - theranostic nanoparticles
KW  - PLGA-PEG
KW  - nanoparticles
KW  - platelet
KW  - activation
KW  - aggregation
KW  - binding
KW  - uptake
KW  - tissue engineering
KW  - Huntington's disease
KW  - siRNA
KW  - microcarriers
KW  - mesenchymal stromal cells
KW  - drug delivery systems
KW  - microfluidics
KW  - microparticles
KW  - BMP-2-microspheres
KW  - hydrogel system
KW  - 17-βestradiol release
KW  - bone regeneration
KW  - osteoporosis
KW  - poly-lactide-co-glycolide
KW  - polylactic acid
KW  - alginate
KW  - ophthalmic drug delivery
KW  - dexamethasone
KW  - PLGA-NPs
KW  - nanomedicine
KW  - gastrointestinal tract
KW  - paclitaxel
KW  - in vivo imaging
KW  - controlled release
KW  - risperidone
KW  - microcapsules
KW  - oleogels
KW  - electron microscopy
KW  - three-dimensional X-ray imaging
KW  - nano-CT
KW  - biodegradable polymers
KW  - hydroxy-stearic acid
KW  - PLGA nanocapsules
KW  - magnetic resonance imaging
KW  - photoluminescence
KW  - magnetic targeting
KW  - multimodal imaging
KW  - theranostics
KW  - silicon
KW  - microsphere
KW  - n/a
N1  - Open Access
N2  - Poly(lactic-co-glycolic acid) (PLGA) is one of the most successful polymers used for producing therapeutic devices, such as drug carriers (DC). PLGA is one of the few polymers that the Food and Drug Administration (FDA) has approved for human administration due to its biocompatibility and biodegradability. In recent years, DC produced with PLGA has gained enormous attention for its versatility in transporting different type of drugs, e.g., hydrophilic or hydrophobic small molecules, or macromolecules with a controlled drug release without modifying the physiochemical properties of the drugs. These drug delivery systems have the possibility/potential to modify their surface properties with functional groups, peptides, or other coatings to improve the interactions with biological materials. Furthermore, they present the possibility to be conjugated with specific target molecules to reach specific tissues or cells. They are also used for different therapeutic applications, such as in vaccinations, cancer treatment, neurological disorder treatment, and as anti-inflammatory agents. This book aims to focus on the recent progress of PLGA as a drug carrier and their new pharmaceutical applications
UR  - https://mdpi.com/books/pdfview/book/3432
UR  - https://directory.doabooks.org/handle/20.500.12854/68416
ER  -