TY  - GEN
AU  - Timothy B.Niewold
TI  - Type I Interferon in Human Autoimmunity
SN  - 978-2-88919-340-0
PY  - 2015///
PB  - Frontiers Media SA
KW  - Multiple Sclerosis
KW  - autoimmune thyroid disease
KW  - systemic lupus erythematosus
KW  - systemic sclerosis
KW  - Interferons
KW  - Sjogren's Syndrome
N1  - Open Access
N2  - The type I interferon system plays a critical role in host defense in health, and a growing body of literature suggests that type I interferon is a critical mediator of human autoimmune disease. Type I interferons function as a bridge between the innate and adaptive immune systems, and as such play an important role in setting thresholds for response against self antigens. Many investigators have focused on the role type I interferons play in autoimmune disease. This fascinating and rapidly growing body of literature encompasses many different autoimmune diseases, including systemic lupus erythematosus, type I diabetes, multiple sclerosis, and others. In this Research Topic, we provide a comprehensive overview of the various roles type I interferons play in autoimmune diseases, with a focus on human immunology
UR  - http://journal.frontiersin.org/researchtopic/1320/type-i-interferon-in-human-autoimmunity
UR  - https://directory.doabooks.org/handle/20.500.12854/61437
ER  -