TY - GEN AU - Dion-Côté,Anne-Marie AU - Barbash,Daniel A. AU - Clark,Andrew G. AU - Lower,Sarah E. TI - Repetitive DNA Sequences SN - books978-3-03928-367-5 PY - 2020/// PB - MDPI - Multidisciplinary Digital Publishing Institute KW - transgene KW - zebra finch KW - transcription KW - endogenous retrovirus KW - transposable element KW - centromere drive KW - arthropods KW - PSR (Paternal sex ratio) KW - Alu KW - gene evolution KW - nuclear rDNA KW - epigenetics KW - heterochromatin KW - alpha satellite KW - Su(Hw) KW - repeated elements KW - karyotype KW - piRNA cluster KW - gene duplication KW - super-Mendelian KW - estrildidae KW - genomic conflict KW - GC-content KW - segregation KW - CENP-A KW - drift KW - germline KW - hobo KW - I element KW - repetitive DNA KW - transposons KW - human satellites KW - retrotransposons KW - genome assembly KW - LTR retrotransposons KW - satellite DNA KW - structural variation KW - selection KW - host genome KW - Uraeginthus cyanocephalus KW - LINE-1 KW - B chromosomes KW - ERV KW - arms race KW - sequence variation KW - secondary structure KW - HeT-A and TART telomeric retrotransposons KW - database KW - genetic conflict KW - coevolution KW - ncRNAs (non coding RNAs) KW - repeat KW - centromeric transcription KW - nucleolus KW - satellite KW - insulator KW - Rhino KW - population genetics KW - centromere KW - genome annotation KW - horizontal transfer KW - rRNA KW - genome elimination KW - genome evolution KW - evolution KW - chromosome evolution KW - genome size KW - genome KW - drosophila KW - transposable elements KW - selfish elements N1 - Open Access N2 - Repetitive DNA is ubiquitous in eukaryotic genomes, and, in many species, comprises the bulk of the genome. Repeats include transposable elements that can self-mobilize and disperse around the genome, and tandemly-repeated satellite DNAs that increase in copy number due to replication slippage and unequal crossing over. Despite their abundance, repetitive DNA is often ignored in genomic studies due to technical challenges in their identification, assembly, and quantification. New technologies and methods are now providing the unprecedented power to analyze repetitive DNAs across diverse taxa. Repetitive DNA is of particular interest because it can represent distinct modes of genome evolution. Some repetitive DNA forms essential genome structures, such as telomeres and centromeres, which are required for proper chromosome maintenance and segregation, whereas others form piRNA clusters that regulate transposable elements; thus, these elements are expected to evolve under purifying selection. In contrast, other repeats evolve selfishly and produce genetic conflicts with their host species that drive adaptive evolution of host defense systems. However, the majority of repeats likely accumulate in eukaryotes in the absence of selection due to mechanisms of transposition and unequal crossing over. Even these neutral repeats may indirectly influence genome evolution as they reach high abundance. In this Special Issue, the contributing authors explore these questions from a range of perspectives UR - https://mdpi.com/books/pdfview/book/2048 UR - https://directory.doabooks.org/handle/20.500.12854/58231 ER -