TY  - GEN
AU  - Marietta Herrmann
AU  - Slavko Mojsilovic
AU  - Jelena Krstic
AU  - Ivana Gadjanski
TI  - Microenvironment-Derived Stem Cell Plasticity
SN  - 978-2-88945-344-3
PY  - 2017///
PB  - Frontiers Media SA
KW  - microenvironment
KW  - stem cells
KW  - tissue regeneration
KW  - immunomodulation
KW  - extracellular vesicles (EVs)
KW  - oxygen tension
KW  - plasticity
KW  - imaging
N1  - Open Access
N2  - Plasticity is the hallmark of stem cells. At the same time, stem cells, like any other cell type, are influenced by their microenvironment and respond to it accordingly. A specific microenvironment is defined by a variety of factors, including biological and chemical factors, cell-cell interactions, but also metabolic and mechanical cues. Such dynamic and specialized microenvironment where the stem cells reside is considered a stem cell niche. Tissue injury as well as malignant tissue alterations lead to changes in the niche influencing the plasticity and biology of residing stem cells. Similarly, the niche changes upon tissue damage, which eventually induces differentiation of stem cells and ultimately regeneration of the tissue
UR  - https://www.frontiersin.org/research-topics/4681/microenvironment-derived-stem-cell-plasticity
UR  - https://directory.doabooks.org/handle/20.500.12854/53417
ER  -