TY  - GEN
AU  - Yan,Liang-Jun
AU  - Yan,Liang-Jun
TI  - Redox Imbalance and Mitochondrial Abnormalities in Kidney Disease
SN  - books978-3-0365-3758-0
PY  - 2022///
CY  - Basel
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - Medicine
KW  - bicssc
KW  - Pharmacology
KW  - diabetic kidney disease
KW  - caloric restriction
KW  - NADH/NAD+
KW  - redox imbalance
KW  - mitochondrial homeostasis
KW  - mitophagy
KW  - oxidative stress
KW  - kidney allograft
KW  - kidney rejection
KW  - ischemia
KW  - acute kidney injury (AKI)
KW  - chronic kidney disease (CKD)
KW  - tricarboxylic acid (TCA) cycle
KW  - mitochondrial metabolism
KW  - mitochondrial redox signaling
KW  - mitochondrial proteins
KW  - oxidative phosphorylation (OXPHOS)
KW  - fatty acid (FA) β-oxidation
KW  - mitochondrial dynamics
KW  - biogenesis
KW  - diabetes
KW  - kidney
KW  - mitochondria
KW  - Oryza sativa
KW  - rice husk
KW  - TCA cycle metabolites
KW  - kidney diseases
KW  - renalase
KW  - chronic kidney disease
KW  - major adverse cardiovascular outcomes
KW  - cadmium
KW  - kidney injury
KW  - renal toxicity
KW  - oxidative damage
KW  - proximal tubule
KW  - controlled oxygenated rewarming
KW  - mitochondrial uncoupling
KW  - rewarming injury
KW  - temperature paradox
KW  - redox
KW  - mitochondrial dysfunction
KW  - SGLT2
KW  - mitochondrial reactive oxygen species
KW  - Warburg effect
KW  - podocytopathies
KW  - mitochondrial oxidative stress
KW  - reactive oxygen species (ROS)
KW  - antioxidant defense
KW  - cell death
KW  - n/a
N1  - Open Access
N2  - The kidney performs important functions in the human body and can inflict either acute kidney injury (AKI) or chronic kidney disease (CKD). AKI can be induced by kidney ischemia, drugs such as cisplatin, and heavy metals such as cadmium and arsenic. CKD can be induced by drugs, heavy metals, hypertension, and diabetes, as well as cancer. Importantly, nearly all kidney disorders have been shown to involve redox imbalance, reductive stress, oxidative stress, and mitochondrial abnormalities such as impaired mitochondrial homeostasis, including disrupted mitophagy and deranged mitochondrial unfolded protein responses. Understanding how these redox-related dysregulated pathways operate may give us new insights into how to design novel approaches to fighting kidney disease. This Special Issue of Biomolecules entitled "Redox imbalance and mitochondrial abnormalities in kidney disease" covers a variety of topics focusing on oxidative stress, mitochondrial dysfunction, and antioxidation enhancement implicated in kidney disease or kidney transplantation
UR  - https://mdpi.com/books/pdfview/book/5361
UR  - https://directory.doabooks.org/handle/20.500.12854/81019
ER  -