TY - GEN AU - Leggat,Peter AU - Frean,John AU - Blumberg,Lucille AU - Leggat,Peter AU - Frean,John AU - Blumberg,Lucille TI - COVID-19: Current Challenges and Future Perspectives SN - books978-3-0365-3119-9 PY - 2022/// CY - Basel PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Medicine KW - bicssc KW - Environmental medicine KW - COVID-19 KW - SARS-CoV-2 KW - hepatitis B and C KW - cirrhosis KW - chronic kidney disease KW - alcohol-related liver disease KW - nonalcoholic steatohepatitis KW - necrosis KW - MDR-TB KW - clinical trials KW - IL-6 inhibitors KW - tocilizumab KW - cytokine release syndrome KW - cytokine storm KW - operational research KW - health systems KW - SORT IT KW - pandemics KW - training KW - pandemic KW - endemic KW - tuberculosis KW - impact KW - control KW - overview KW - malaria KW - preparedness KW - Africa KW - emergency KW - fecal calprotectin KW - bowel perforation KW - D-Dimer KW - thrombosis KW - ischemia KW - efficacy KW - safety KW - kaletra KW - lopinavir/ritonavir KW - meta-analysis KW - coronavirus KW - SARS-CoV-1 KW - MERS KW - SARS KW - influenza KW - healthcare worker KW - healthcare personnel KW - general practitioners KW - medical doctor KW - heart transplant KW - CMV KW - Chagas disease KW - infection KW - severity KW - respiratory viruses KW - coinfections KW - health care workers KW - Philippines KW - rhinovirus KW - severe acute respiratory syndrome coronavirus 2 KW - plasmodium falciparum KW - differential diagnosis KW - cognitive bias KW - diagnostic reasoning KW - recurrence KW - reinfection KW - Bangladesh KW - Kenya KW - Nairobi KW - presumptive tuberculosis KW - TB treatment outcomes KW - HIV KW - antiretroviral therapy KW - EpiCollect5 KW - Malawi KW - Lilongwe KW - Zimbabwe KW - Harare KW - real-time operational research KW - ethics KW - research capacity building KW - India KW - Nepal KW - post-acute COVID-19 syndrome KW - COVID-19 vaccines KW - mortality KW - epidemiology KW - public health KW - healthcare workers KW - attitudes KW - perceptions KW - knowledge KW - n/a N1 - Open Access N2 - On March 11, 2020, the World Health Organization declared COVID-19 a global pandemic and the disease now affects nearly every country and region. Caused by SARS-CoV-2, COVID-19 presents significant challenges to health systems and public health in both hemispheres as well as to the economies of each country. The morbidity and mortality due to infections caused by SARS-CoV-2 have been significant despite the short duration since its discovery and initially overwhelmed many hospitals and clinics. It influences everyone, and countermeasures have been dramatic in their impact on employment, social systems, and mental health. This Special Issue provides an avenue for authors from various disciplines to provide feedback on our responses and preparedness to COVID-19 globally as well as to disseminate critical information about the SARS-CoV-2 virus and the associated COVID-19 pandemic. It consists of 22 peer-reviewed papers that cover worldwide perspectives encompasses the following: Original articles about COVID-19 (including epidemiology, modelling, clinical data, treatment, prevention, countermeasures, impacts on tropical regions, response, and preparedness);Original articles about SARS-CoV-2 (microbiology, virology, transmission, pathology, and vaccinology);Perspectives about COVID-19 and SARS-CoV-2 (comparisons with past coronavirus outbreaks, impactful local initiatives, novel responses, and commentaries);Reviews on COVID-19 (based on systematic and narrative reviews);and Innovations (vaccine development, drug trials, and original countermeasures) UR - https://mdpi.com/books/pdfview/book/5094 UR - https://directory.doabooks.org/handle/20.500.12854/81066 ER -