TY - GEN AU - Tampa,Mircea AU - Neagu,Monica AU - Caruntu,Constantin AU - Georgescu,Simona Roxana AU - Tampa,Mircea AU - Neagu,Monica AU - Caruntu,Constantin AU - Georgescu,Simona Roxana TI - Personalized Medicine in the Field of Inflammatory Skin Disorders SN - books978-3-0365-3573-9 PY - 2022/// CY - Basel PB - MDPI - Multidisciplinary Digital Publishing Institute KW - Medicine KW - bicssc KW - sea-buckthorn seed oil KW - long-chain fatty acids KW - skin dysplastic keratinocytes KW - UVA KW - CD36 KW - SR-B2 KW - atopic dermatitis KW - eczema KW - JAK inhibitors KW - systematic review KW - meta-analysis KW - evidence-based medicine KW - immune-mediated skin diseases KW - target therapy KW - skin conditions and systemic inflammatory diseases KW - systemic sclerosis KW - biomarker KW - calumenin KW - S100A6 KW - cytohesin 2 KW - cannabinoids KW - inflammation KW - gut-lung-skin barrier KW - signaling pathways KW - inflammatory biomarkers KW - psoriasis vulgaris KW - prevalence KW - comorbidities KW - risk factors KW - systemic lupus erythematous KW - lupus nephritis KW - lipid peroxidation KW - DNA oxidation KW - oxidized proteins KW - carbohydrate oxidation KW - antioxidative stress strategies KW - biomarkers KW - IgY KW - psoriatic dermatitis KW - imiquimod KW - C57 BL/6 mice KW - alginate KW - biomaterial KW - dressing KW - fibers KW - hydrogel KW - nanofibers KW - commercially available KW - wound care KW - wound healing KW - cutaneous melanoma KW - epigenetic regulation KW - drug resistance KW - therapeutic targets KW - epigenetic therapy KW - immune response KW - Sutton nevi KW - halo nevi KW - skin tumor KW - psoriasis KW - proteome analysis KW - estrogen KW - menopause KW - cSCC KW - AK KW - sialylation KW - sialyltransferase KW - sialidase KW - COVID-19 KW - pyoderma gangrenosum KW - immunosuppression KW - cyclosporine KW - corticosteroids KW - autoinflammatory disease KW - androgenic alopecia KW - clinical trial KW - hair density KW - platelet-rich plasma KW - n/a N1 - Open Access N2 - Skin inflammation is associated with a wide range of conditions which represent major health issues worldwide. Skin and mucosal surfaces represent the primary interface between the human body and the environment, susceptible to numerous factors whose action results in diseases produced by chemical substances, mechanical trauma, microbial agents, radiation, etc. Inflammation, a complex network of interactions between soluble molecules and cells, represents the main modality of the skin's response to injuries. Numerous studies have revealed close links between chronic inflammation, oxidative stress, and carcinogenesis. Chronic inflammation induces the activation of various cell types and an increase in the production of reactive oxygen species, promoting the initiation of a malignant process. Identifying specific biomarkers is essential for understanding molecular mechanisms and developing therapies appropriate to the patient's characteristics.Personalized medicine is an emerging field of medicine that has the potential to predict which therapy will be safe and efficacious for specific patients using an individual's genetic profile to guide decisions regarding the diagnosis, treatment, as well as prevention of disease. This book gathers articles that present recent advancements in research involving the mechanisms that underlie the development of inflammatory skin disorders, skin and mucosal inflammation in general UR - https://mdpi.com/books/pdfview/book/5182 UR - https://directory.doabooks.org/handle/20.500.12854/81151 ER -