TY  - GEN
AU  - Dwight E.Heron
AU  - John Austin Vargo
TI  - Clinical Application of Stereotactic Body Radiotherapy (SBRT): Cranium to Prostate
SN  - 978-2-88919-846-7
PY  - 2016///
PB  - Frontiers Media SA
KW  - Stereotactic radiosurgery
KW  - Gynecologic
KW  - Central Nervous System
KW  - Non small cell lung cancer
KW  - head and neck
KW  - stereotactic body radiation therapy
KW  - Prostate
KW  - Adrenal metastases
N1  - Open Access
N2  - Stereotactic radiosurgery is a relatively recent radiation technique initially developed using a frame-based system in 1949 by a Swedish neurosurgeon, Lars Leksell, for lesions not amendable to surgical resection. Radiosurgery is founded on principles of extreme radiation dose escalation, afforded by precise dose delivery with millimeter accuracy. Building upon the success of frame-based radiosurgery techniques, which were limited to cranial tumors and invasive head-frame placement, advances in radiation delivery and image-guidance have lead to the development of stereotactic body radiotherapy (SBRT). SBRT allows for frameless delivery of dose distributions akin to frame-based cranial stereotactic radiosurgery to both cranial and extra-cranial sites and has emerged as a important treatment strategy for a variety of cancers from the cranium to prostate. Herein we highlight ongoing investigations for the clinical application of SBRT for a variety of primary and recurrence cancers aimed at examining the growing clinical evidence supporting emerging roles for SBRT in the ever growing oncologic armamentarium
UR  - http://journal.frontiersin.org/researchtopic/3041/clinical-application-of-stereotactic-body-radiotherapy-sbrt-cranium-to-prostate
UR  - https://directory.doabooks.org/handle/20.500.12854/43398
ER  -