TY  - BOOK
AU  - Carnazza,Santina
AU  - Guglielmino,Salvatore
TI  - Phage display as a tool for synthetic biology
T2  - Nanotechnology science and technology series
SN  - 9781617618253
AV  - TP248.27.M53 C37 2010eb
U1  - 660.6 22
PY  - 2010///
CY  - New York
PB  - Nova Science Publishers
KW  - Bacteriophages
KW  - Microbial biotechnology
KW  - Synthetic biology
KW  - Protein engineering
KW  - Nanotechnology
KW  - Biomimetic Materials
KW  - chemical synthesis
KW  - Nanostructures
KW  - Protein Engineering
KW  - Synthetic Biology
KW  - Biotechnologie microbienne
KW  - Biologie synthétique
KW  - Technologie des protéines
KW  - Bactériophages
KW  - Nanotechnologie
KW  - SCIENCE
KW  - Biotechnology
KW  - bisacsh
KW  - fast
KW  - Electronic books
N1  - Includes bibliographical references and index; Synthetic biology applications in nanobiotechnology -- The "never born proteins" -- Protein engineering and directed evolution -- In vitro and biological display technologies -- Phage display for directed molecular evolution -- Antibody phage -- Phage as bioselective probes -- Phage-derived nanomaterials -- Phage perspectives in nanobiotechnology
N2  - Phage display can be considered as a practical realization of an artificial chemical evolution. As such, it is an useful tool for in vitro protein evolution, aimed to identifying new receptors and natural ligands for "orphan receptors", drug discovery (peptides might act as enzyme inhibitors and receptor agonists or antagonists, or otherwise modulate the enzyme/receptor's biological effect), "epitope discovery" (a new approach to disease diagnosis and vaccine development), design of DNA-binding proteins, source of new materials, antibody phage and recombinant phage probes, next-generation nano-electronics, targeted therapy, molecular imaging, gene delivery and phage-display vaccination. All this can be regarded as a kind of synthetic biology in that it involves the reshaping and redirecting of natural molecular systems, phage, typically using the tools of protein and genetic engineering.--Provided by publisher
UR  - https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=341670
ER  -