TY - BOOK AU - Kenakin,Terrence P. TI - A pharmacology primer: theory, applications, and methods SN - 0080465307 AV - RM301.25 .K46 2006eb U1 - 615.1 22 PY - 2006/// CY - Amsterdam, Boston PB - Elsevier Academic Press KW - Pharmacology KW - Drugs KW - Chemicals KW - Physiological effect KW - Dose-response relationship KW - Receptors, Drug KW - physiology KW - Pharmaceutical Preparations KW - Dose-Response Relationship, Drug KW - methods KW - Pharmacologie KW - Médicaments KW - Produits chimiques KW - Effets physiologiques KW - Relations dose-effet KW - pharmacology KW - aat KW - MEDICAL KW - Drug Guides KW - bisacsh KW - Nursing KW - Pharmacy KW - fast KW - Pharmakologie KW - gnd KW - Electronic books N1 - Includes bibliographical references and index; What is Pharmacology? -- How Different Tissues Process Drug Response -- Drug Receptor Theory -- Pharmacological Assay Formats: Binding -- Agonists: The Measurement of Affinity and Efficacy in Functional Assays -- Orthosteric Drug Antagonism -- Allosteric Drug Antagonism -- The Process of Drug Discovery -- Target- and System-based Strategies for Drug Discovery -- Hit to Drug: Lead Optimization -- Statistics and Experimental Design -- Selected Pharmacological Methods -- Glossary of Pharmacological Terms -- Appendices: -- Statistical Tables -- Mathematical Fitting Functions N2 - The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments. *Over 30 new figures and tables *More human interest information to provide readers with historical facts on pharmacology research *New section on therapeutics to help identify diseaes and drug treatments *New section on new biological concepts relevant to pharmacological research (i.e., systems biology) *New study sections organized with ASPET and other international pharmacology organizations *New coverage of pharmacokinetics and drug disposition UR - https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=182185 ER -