TY - BOOK AU - Mancher,Michelle AU - Leshner,Alan I. ED - National Academies of Sciences, Engineering, and Medicine (U.S.). TI - Medications for opioid use disorder save lives T2 - Consensus study report of the National Academies of Sciences, Engineering, Medicine SN - 9780309486514 AV - RC568.O45 U1 - 615.7/822 23 PY - 2019///] CY - Washington, DC PB - National Academies Press KW - Opioid abuse KW - Treatment KW - United States KW - Drug addicts KW - Rehabilitation KW - Opioids KW - Overdose KW - Brain KW - Diseases KW - Prevention KW - Government policy KW - Methadone maintenance KW - Buprenorphine KW - Therapeutic use KW - Naloxone KW - Naltrexone KW - Drugs KW - Opiate Substitution Treatment KW - Opioid-Related Disorders KW - drug therapy KW - Drug Users KW - Drug Overdose KW - Toxicomanie aux opiacés KW - Traitement KW - États-Unis KW - Toxicomanes KW - Réadaptation KW - Opioïdes KW - Surdosage KW - Cerveau KW - Maladies KW - Méthadone KW - Emploi en thérapeutique KW - Buprénorphine KW - Médicaments KW - fast KW - Electronic books N1 - Includes bibliographical references; Introduction -- The effectiveness of medication-based treatment for opioid use disorder -- Treatment with medications for opioid use disorder in different populations -- Medications for opioid use disorder in various treatment settings -- Barriers to broader use of medications to treat opioid use disorder -- Appendixes N2 - The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already exist--like evidence-based medications--are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed UR - https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=2186517 ER -