TY  - BOOK
AU  - Mohr,Stephanie Elizabeth
TI  - First in fly: Drosophila research and biological discovery 
SN  - 9780674984721
AV  - QL537.D76 M65 2018eb
U1  - 595.77/4 23
PY  - 2018///
CY  - Cambridge, Massachusetts
PB  - Harvard University Press
KW  - Drosophila melanogaster
KW  - Genetics
KW  - Physiology
KW  - Animal models in research
KW  - genetics
KW  - physiology
KW  - Drosophila Proteins
KW  - Models, Animal
KW  - Génétique
KW  - Physiologie
KW  - Modèles animaux dans la recherche
KW  - SCIENCE
KW  - Life Sciences
KW  - Zoology
KW  - General
KW  - bisacsh
KW  - SCIENCE / Life Sciences / Genetics & Genomics
KW  - Science
KW  - eflch
KW  - fast
KW  - Genetik
KW  - gnd
KW  - Taufliege
KW  - Tiermodell
KW  - ukslc
KW  - Electronic books
N1  - Includes bibliographical references and index; Maps -- Change -- Communication -- Size -- Direction -- Difference -- Defenses -- Behavior -- Coordination -- Continuity
N2  - A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. This book notes insights uncovered by investigators using this model organism. The author draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.--
UR  - https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1712993
ER  -