TY - BOOK AU - Becker,Richard C. AU - Spencer,Fredrick A. TI - Antithrombotic therapy in the prevention of ischemic stroke T2 - Oxford American pocket notes SN - 9780199774449 AV - RC388.5 .B43 2010eb U1 - 616.81061 22 PY - 2010/// CY - Oxford, New York PB - Oxford University Press KW - Transient ischemic attack KW - Chemotherapy KW - Prevention KW - Fibrinolytic agents KW - Ischemic Attack, Transient KW - drug therapy KW - prevention & control KW - Fibrinolytic Agents KW - Accident ischémique transitoire KW - Chimiothérapie KW - Fibrinolytiques KW - HEALTH & FITNESS KW - Diseases KW - General KW - bisacsh KW - MEDICAL KW - Clinical Medicine KW - Evidence-Based Medicine KW - Internal Medicine KW - fast KW - Electronic books N1 - Includes bibliographical references; Cover; Contents; Introduction and Epidemiology; Pathophysiology; Regulatory Factors in Thrombus Formation; Cellular Interactions in Atherothrombosis; Classification of Stroke; Managing Risk Factors for Recurrent Stroke; Antithrombotic Therapy for Prevention of Recurrent TIA and Stroke; Aspirin; Mechanism of Action; Pharmacokinetics; Adverse Effects; Aspirin Administration in Clinical Practice; Secondary Prevention of Vascular Events and Stroke; Aspirin Dosing in Prevention of Recurrent TIA/Stroke; Thienopyridines (Clopidogrel, Ticlopidine, and Prasugrel); Mechanism of Action; Clopidogrel; PharmacokineticsAbsorption; Adverse Effects; Prevention of Vascular Events; Ticlopidine; Prasugrel; Dipyridamole, Extended-Release Dipyridamole/Aspirin Combination (Aggrenox); Mechanism of Action; Pharmacokinetics; Pharmacodynamics; Adverse Effects; Administration in Older Patients; Clinical Experience; Cilostazol; References N2 - Stroke is the most common cause of adult mortality in the United States. Antithrombotic agents form the mainstay of stroke prevention. Aspirin produces a modest reduction in the risk of second stroke and transient ischemic attack (TIA, mini-stroke) and is widely recommended for initial therapy. The thienopyridines (Ticlid) and clopodogrel (Plavix) are alternatives for secondary prevention in patients who do not respond to or cannot take aspirin. They are no more effective than aspirin and have been associated with thrombotic thrombocytopenic purpura. The combination of aspirin and extended-rel UR - https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=669957 ER -