Derivatization in Analytical Chemistry
Material type:
ArticleLanguage: English Publication details: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022Description: 1 electronic resource (210 p.)ISBN: - books978-3-0365-4255-3
- 9783036542560
- 9783036542553
- Research & information: general
- Chemistry
- Analytical chemistry
- tyrosine kinase inhibitors
- chloranilic acid
- charge-transfer reaction
- 96-microwell spectrophotometric assay
- high-throughput pharmaceutical analysis
- biogenic amines
- Lycium barbarum L
- HPLC
- derivatization
- amino acids
- esterification
- GC-MS
- pentafluoropropionic anhydride
- stability
- toluene
- pigment
- linseed oil
- derivatisation
- quantification
- P/S ratio
- A/P ratio
- ∑D
- GC-MS
- ureide
- BSTFA
- creatine
- creatinine
- silylation
- TMS
- validation
- low-molecular-weight thiols
- human serum albumin
- α-lipoic acid
- blood plasma
- monobromobimane
- reduction
- sodium borohydride
- high-performance liquid chromatography
- fluorescence detection
- taurine
- glutamine
- clams
- high-resolution mass spectrometry
- nerve agents
- methylation
- chemical warfare agents
- sarin
- Novichoks
- 2-naphthalenethiol
- sulforaphane
- HPLC-UV/Vis
- pharmacokinetics
- acetonitrile-related adducts
- acetylenic lipids
- double and triple bond localization
- in-source derivatization
- mass spectrometry
- acetazolamide
- carbonic anhydrase
- enhancement
- inhibition
- pentafluorobenzyl bromide
- chiral metabolomics
- rice water
- d-amino acids
- enantiomer separation
- dimethyl labeling
- homocysteine thiolactone
- homocysteine
- zone fluidics
- o-phthalaldehyde
- fluorosurfactant-modified gold nanoparticles
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Derivatization is one of the most widely used sample pretreatment techniques in Analytical Chemistry and Chemical Analysis. Reagent-based or reagent-less schemes offer improved detectability of target compounds, modification of the chromatographic properties and/or the stabilization of sensitive compounds until analysis. Either coupled with separation techniques or as a "stand alone" analytical procedure, derivatization offers endless possibilities in all aspects of analytical applications.
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