Advances in medicine and biology. Volume 27 / edited by Leon V. Berhardt.

Includes bibliographical references and index.

Print version record.

ADVANCES IN MEDICINE AND BIOLOGY. ; ADVANCES IN MEDICINE AND BIOLOGY. ; Contents ; Preface ; Recent Advancement of Ceramics in Biomedical Research ; Abstract ; 1. Introduction ; 1.1. Ceramic Implants ; 1.1.1. First Generation Ceramic Materials ; 1.1.2. Second Generation Ceramic Materials ; 1.1.3. Third Generation Ceramic Materials ; 2. Ceramics as Local Drug and Other Organic Moiety Delivery System ; 3. Ceramics in Dental Applications ; 3.1. Classification of Dental Ceramics ; 4. Ceramic Hip and Knee Replacement ; 5. Ceramics as Bone Void Filler Material.

6. Ceramic as Coating of Metallic Implants 7. Ceramics in Cardiovascular Application ; 8. Ceramics in Craniofacial and Maxillofacial Application ; 9. Ceramics n Ear Reconstruction ; 10. Ceramics in Spinal Surgery ; 11. Ceramics as Orbital Implants ; 11.1. Ideal Orbital Implant ; 11.2. Biomaterial Characteristics and Biocompatibility Requirements for Orbital Implants ; Conclusion ; Acknowledgments ; Reviewed by ; References ; The Role of HtrA as a Chaperone and Protease in Bacterial Pathogenesis ; Abstract ; Introduction ; Background ; History; Biochemistry ; Structure ; The HtrA Hexamer.

The PDZ Domains HtrA12/24 ; Functional Implications of Structure; Role of Membrane Lipids; HtrA Self-Regulation ; Molecular Mechanisms of Regulation ; The SigmaE Regulatory System ; The Cpx Regulatory System ; The Bae Regulatory System ; Bioinformatics and Genetic Diversity ; HtrA Substrates ; HtrA Substrate Specificity for Proteolysis ; Chaperone Substrate Specificity ; HtrA Substrates in Pathogenesis ; Conclusion ; References ; Vasopressin, Diabetes Insipidus, the Syndrome of Inappropriate Antidiuresis and Hyponatraemia ; Abstract ; Osmoregulation and Vasopressin ; Diabetes Insipidus.

Hypothalamic Diabetes Insipidus Nephrogenic Diabetes Insipidus ; Dipsogenic Diabetes Insipidus ; Investigation of Diabetes Insipidus ; Adipsic Diabetes Insipidus ; Treatment of Diabetes Insipidus ; The Syndrome of Inappropriate Antidiuresis ; Causes of SIAD ; Aetiology of SIAD; Diagnosis of SIAD ; Differential Diagnosis of SIAD ; Hyponatraemia ; Prevalence and Effects of Hyponatraemia; Differential Diagnosis of Hyponatraemia ; Management of Hyponatraemia; Future Management of Hyponatraemia ; Conclusion; References ; The UPR, Cellular and Systemic Iron Homeostasis ; Abstract; Introduction.

Visiting the Endoplasmic ReticulumStressing Out the ER and the Unfolded Protein Response ; Is the UPR Changing the Paradigm of Disease? HFE Hemochromatosis as Model; The UPR-Iron Metabolism Axis: Putative Physiological Significance ; The UPR-Iron Metabolism Axis: Possible Link to Pathological Conditions ; Conclusion ; Acknowledgments ; References; The Unfolded Protein Response in Renal Transplantation ; Abstract ; Abbreviations ; Introduction ; The Endoplasmic Reticulum and Endoplasmic Reticulum Stress; Characterization of the Unfolded Protein Response.

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