Stem cell therapy and uses in medical treatment / Prasad S. Koka, editor.

Includes bibliographical references and index.

Description based on print version record.

STEM CELL THERAPY AND USES IN MEDICAL TREATMENT ; STEM CELL THERAPY AND USES IN MEDICAL TREATMENT; Contents; Preface ; Stem Cell-Based Therapies: The Roadmap to the Clinic ; Abstract ; 1. Introduction ; 2. The Conditions under Which Clinical Trials of Stem Cell-Based Therapies with and without Alternative Treatment Options Can Be Justified ; 3. Safety as an Obstacle to Advance Stem Cell-Based Therapies from Laboratories to Patient's Bedside ; 4. Results That Have to Be Shown in Animals in Order to Justify Clinical Trials of Stem Cell-Based Therapies.

5. The Design of the Clinical Trials of Stem Cell-Based Therapies and the Ethical Problems Raised by Randomised Clinical Trials When Alternative Treatments Exist 6. Other Obstacles to Advancing Stem Cell-Based Therapies from Laboratory Research to Patient's Bedside ; Conclusions ; Acknowledgments ; References ; Survival and Differentiation of Syngeneic Bone Marrow-Derived Mononuclear Cells in Rat Intervertebral Discs ; Abstract ; Introduction ; Material and Methods ; Isolation and Labelling of BMC ; Intervertebral Disc Transplantation and Specimen Preparation ; Cell Culture ; Histology.

Cell Counting Immune Fluorescence Staining ; Ethics ; Statistical Analyses; Results ; Cell Culture; Histology ; Number of Cells; Cell Differentiation; Discussion; Conclusion; Acknowledgments ; References ; Current Therapies for Multiple Sclerosis: Stem Cells or Immunomodulators? ; Abstract ; Introduction; Stem Cell Therapy for MS ; Neuronal Stem Cells ; Bone Marrow-Derived Haematopoietic Stem Cells ; Immunomodulatory Drugs ; Interferon -Based Therapies ; Copaxone®: Laboratory and Clinical Findings ; GA-Related Copolymers and Their Mechanisms ; Mitoxantrone ; Natalizumab.

Combinational Therapy Future Perspectives: Candidate Therapies ; Ongoing Clinical Trials ; Concluding Remarks ; References ; Stem Cell Transplantation Modulates mRNA Gene Expression Profile in Doxorubicin-Induced Cardiomyopathy ; Abstract ; Introduction ; Materials and Methods ; Animal Experiments and Study Design ; Isolation, Expansion and Labeling of Stem Cells ; Cell Transplantation ; Assay of VEGF, bFGF, IGF and ANP mRNA Profile ; Statistical Anaylsis ; Results ; Discussion ; Principle Limitations of Our Study ; Conclusion ; Acknowledgments ; References.

Human Somatic Cell Nuclear Transfer and Parthenogenesis: Preliminary Indian Experience Abstract ; Introduction ; Study Subjects and Methods ; Human Ethics and Oocyte Donation; Materials ; Preparation of Karyoplast ; Preparation of Cytoplast and Viewing of Spindle ; Somatic Cell Nuclear Transfer ; Parthenogenesis ; Results ; Viewing of Eggs under POLSCOPE ; Somatic Cell Nuclear Transfer ; Parthenogenesis ; Discussion ; Acknowledgments ; References; Human Cord Blood Stem Cell Applications in Cell Therapy ; Abstract ; Summary for Lay Readers ; Introduction.

English.

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