Monoclonal antibody production / Committee on Methods of Producing Monoclonal Antibodies, Institute for Laboratory Animal Research, National Research Council.

Contributor(s):

National Research Council (U.S.)

Material type: Text

TextPublication details: Washington, D.C. : National Academy Press, 1999.Description: 1 online resource (xiv, 59 pages) : illustrations, chartsContent type:

text

Media type:

computer

Carrier type:

online resource

ISBN:

0585082421
9780585082424

Subject(s): Genre/Form:

Additional physical formats: Print version:: Monoclonal antibody production.DDC classification:

971.967

LOC classification:

QR186.85 .I55 1999eb

NLM classification:

QW 575.5 A6

Online resources:

Click here to access online

Contents:

Generation of hybridomas: permanent cell lines secreting monoclonal antibody -- In vitro production of monoclonal antibody -- Scientific needs for mouse ascites production of mAb -- Summary of advantages and disadvantages of in vitro and in vivo methods -- Large-scale production of monoclonal antibodies -- Animal-welfare issues related to the ascites method for producing monoclonal antibodies -- Conclusions and recommendations.

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