Mathematical modeling, clustering algorithms and applications / Caroline L. Wilson, editor.

Includes bibliographical references and index.

Description based on print version record and CIP data provided by publisher.

""MATHEMATICAL MODELING, CLUSTERING ALGORITHMS AND APPLICATIONS""; ""MATHEMATICAL MODELING, CLUSTERING ALGORITHMS AND APPLICATIONS ""; ""CONTENTS ""; ""PREFACE ""; ""DRUG RELEASE KINETICS FROM EXTENDED RELEASE ORAL DRUG DELIVERY SYSTEMS: MATHEMATICAL MODELING USING VARIOUS APPROACHES ""; ""Abstract ""; ""Introduction ""; ""Extended Release Drug Delivery Systems""; ""Diffusion Controlled Systems ""; ""Reservoir Devices""; ""Matrices""; ""Erosion Controlled Systems ""; ""Swelling Controlled Systems""; ""Osmotic Controlled Systems ""; ""Modeling of Drug Release Kinetics ""

""Higuchian Model """"Peppas and Related Models ""; ""Deborah Mode ""; ""Hopfenberg and Related Models ""; ""Cube Root and Related Models ""; ""Convective-Diffusion Model ""; ""Flanagan Model ""; ""Baker & Lonsdale Model ""; ""Weibull Model ""; ""Zero-order Kinetic Model ""; ""First-Order Kinetic Model ""; ""Second-Order Kinetic Model ""; ""Software for Drug Release Kinetics ""; ""Dissolution Profile Comparisons ""; ""Ratio Test Procedures""; ""Mean Dissolution Time (MDT)""; ""Dissolution Efficiency (DE%) ""; ""Pairwise Procedures ""; ""Difference Factor (f1) ""

""Similarity Factor (f2) """"Rescigno Indices ""; ""Maximum Distance (DMax) ""; ""Difference of Area under the Profiles (dauc) ""; ""Mean Distance (D1) ""; ""Area between the Profiles (DABC) ""; ""Mean Squared Distance (D2) ""; ""Model-Dependent Techniques ""; ""Anova Methods ""; ""Dissolution Correction Formulae ""; ""Validation of Correction Factors ""; ""Epilogue ""; ""Acknowledgments ""; ""References ""; ""MATHEMATICAL MODELING OF NANOCRYSTALLINE AND AMORPHOUS DRUGS RELEASE AND GASTRO-INTESTINAL ABSORPTION FROM POLYMERIC PARTICLES ""; ""Abstract ""; ""1. Introduction ""

""2. Mathematical Modeling """"2.1. In Vivo Drug Release, Absorption, Distribution, Metabolism and Elimination ""; ""2.2. Evaluation of the Model Parameters ""; ""2.2.1. Release System Parameters""; ""2.2.2. Pharmacokinetics Constants ""; ""2.2.2.1. Availability of Plasma Concentration Data ""; ""2.2.2.2. Plasma Concentration Data not Available""; ""3. Simulations ""; ""4. Conclusion ""; ""References ""; ""MATHEMATICAL MODELING OF DRUG RELEASE FROM PHARMACEUTICAL DOSAGE FORMS ""; ""1. Introduction ""; ""2. Drug Release Mechanisms ""; ""3. Mathematical Theories and Models""

""4. Drug Release from Monolithic and Multiple Unit Dosage Forms """"5. Mathematical Analysis ""; ""6. Modeling Techniques Based on Artificial Inteligence""; ""7. Conclusion ""; ""List of Abbreviations""; ""References ""; ""COMPUTER MODELING OF SYNCHRONIZATION OF PROLIFERATIVE EPIDERMIS ACTIVITY SELF-OSCILLATIONS IN PSORIATIC LESIONS WITH AN EXTERNAL PERIODIC FORCE ""; ""Abstract ""; ""Introduction""; ""Main Part ""; ""1. Base Mathematical Model ""; ""Hypothesis of a Psoriatic Lesion Development with Involving of T-cells ""; ""Model Description and Analysis ""

English.

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