Field cancerization : basic science and clinical applications / editor, Gabriel D. Dakubo.

Includes bibliographical references and index.

Description based on print version record.

""CANCER ETIOLOGY, DIAGNOSIS AND TREATMENTS""; ""Contents""; ""Preface""; ""Part I -- Mechanisms of Field Cancerization""; ""Expanding Supercompetitors as a Mechanism of Field Cancerization""; ""The Multistep Field Cancerization Theory of Carcinogenesis""; ""Development of Tumor Stem Cells: Implication in Field Cancerization""; ""Part II -- Epedemiological Aspects of Field Cancerization""; ""Epidemiology of Synchronous and Metachronous Type Multiple Primary Neoplasms""; ""Field Cancerization in Derivatives of the Embryonic Foregut: An Observation Based on Epidemiological Patterns""

""Part III � Clincal and Molecular Aspects of Field Cancerization in Specific Tissues""""Field Cancerization and Oral Leukoplakia""; ""Field Cancerization in Head and Neck Squamous Cell Carcinoma with Focus on Second Primary Tumors""; ""Field Cancerization in Esophageal Epithelia Demonstrated by Telomere Shortening and Chromosomal Instability""; ""Field Cancerization in Mammary Tissues""; ""Field Cancerization in Gastric Cancer""; ""Field Cancerization in Colorectal Cancer""; ""Epigenetic Changes in Hepatic Tissues: Evidence of Field Cancerization""

""Molecular Genetic Alterations in Preneoplastic and Neoplastic Lesions of the Gallbladder""""Field Cancerization in Intraductal Papillary Mucinous Neoplasia of the Pancreas""; ""Field Cancerization in Urothelial Carcinomas of the Upper Urinary Tract""; ""Clonality of Multifocal Urothelial Cancer and Field Cancerization""; ""Evidence of Skin Field Cancerization""; ""Management of Field Cancerization: The Case of Actinic Keratosis""; ""Field Cancerization in Endometrial Carcinoma""; ""Field Cancerization in Vulvar, Vaginal and Cervical Epithelia""; ""Molecular Signatures in Ovarian Cancer""

""Epigenetic Changes in Prostatic Tissues: Evidence of Field Cancerization""""Epigenetic Mechanisms in Solid Tumours of Infancy and Childhood""; ""Epigenetics in Hematological Malignancies""; ""Part IV � Biomarker Development and Therapy Targeting of Epigenetics""; ""Molecular Signatures as Cancer Biomarkers: Methodologic Issues in Discovery, Validation, Qualification, and Standardization""; ""Chemoprevention Targeting Epigenetic Changes in Cancer""; ""Contributors""; ""Index""

English.

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