Acute rejection : risk factors, management and complications / Takumi Kobayashi, Riku Arai, editors.

Includes bibliographical references and index.

ACUTE REJECTION: RISK FACTORS, MANAGEMENT AND COMPLICATIONS -- ACUTE REJECTION: RISK FACTORS, MANAGEMENT AND COMPLICATIONS -- Library of Congress Cataloging-in-Publication Data -- Contents -- Preface -- Chapter 1: HLA and Non-HLA Genes Polymorphisms: Susceptibility and Severity in Tunisian Patients with Rheumatoid Arthritis -- Abstract -- 1. Introduction -- 2. Evaluation of Genetic Predisposition to RA -- 2.1. Prevalence of RA -- 2.2. Familial Clustering Studies -- 2.3. Twins Studies -- 3. Identification of Candidate Genes -- 3.1. Linkage Studies

3.2. Candidate Gene Association Studies4. Results of Linkage Studies in RA -- 5. HLA Association With RA -- 6. Non HLA Candidate Genes Case-control Studies -- 6.1. Protein Tyrosine Phosphatase Non-Receptor, Type 22 (PTPN22) -- 6.2. Tumor Necrosis Factor Receptor Type 2 (TNF-R2) -- 6.3. Peptidyl Arginine Deiminase 4 (PADI 4) -- 6.4. Fc γ Receptor IIIa (FcγRIIIa) -- 6.5. Interleukin 1 Receptor Antagonist (IL-1Ra) -- 6.6. Cytotoxic T Lymphocyte-Associated Antigen-4 (CTLA-4) -- 6.7. Apo-1/Fas (CD95) -- 6.8. Adhesion Molecules -- 7. Patients and Methods

7.1. Patients and Controls7.2. Methods -- 7.3. Statistical Methods -- 8. Results -- 8.1. HLA Typing -- a/ DRB1 Genotyping -- b/ DRB1*04 Sub-typing -- 8.2. PTPN22 Genotyping -- 8.3. CTLA-4 Genotyping -- 8.4. Apo-1/Fas Genotyping -- 8.5. FcγR Genotyping -- 8.6. Adhesion Molecules Genotyping -- 8.7. IL1 Family Polymorphisms Genotyping -- a/ IL1α (C/T -889) -- b/ IL1Ra (Intron 2) -- c/ IL1β C/T -511 and C/T +3954 -- 9. Discussion -- Conclusion -- Acknowledgment -- References

Chapter 2: Mechanisms, Management and Consequences of Acute Cellular and Antibody Mediated Rejection in Solid Organ and Reconstructive TransplantationAbstract -- 1. Acute Rejection -- 2. Kidney Transplantation -- 2.1 The Banff Classification -- 2.2 Acute Antibody-Mediated Rejection in Kidney Transplantation -- 2.3 Acute T-Cell-Mediated Rejection in Kidney Transplantation -- 2.3.1. Steps in TCMR � 3 Signals [12] -- 3. Pancreas Transplantation -- 3.1 The Banff Classification -- 3.2 Acute Antibody-Mediated Rejection in Pancreas Transplantation

3.3 Acute T-Cell-Mediated Rejection in Pancreas Transplantation4. Liver Transplantation -- 4.1 Banff Schema for Grading of Liver Allograft Rejection -- 4.2 Acute Antibody-Mediated Rejection in Liver Transplantation -- 4.3 Acute T-Cell-Mediated Rejection in Liver Transplantation -- 5. Intestinal and Multivisceral Transplantation -- 5.2 Acute Antibody-Mediated Rejection in Intestinal Transplantation -- 5.3 Acute T-Cell-Mediated Rejection in Intestinal Transplantation -- 6. Vascularized Composite Allotransplantation

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