Breast cancer : risk assessment, treatment and new developments / Wendell Armstrong, editor.

Online resource; title from PDF title page (EBSCO, viewed August 17, 2016)

Includes bibliographical references and index.

BREAST CANCER RISK ASSESSMENT, TREATMENT AND NEW DEVELOPMENTS ; BREAST CANCER RISK ASSESSMENT, TREATMENT AND NEW DEVELOPMENTS ; CONTENTS ; PREFACE ; Chapter 1 BREAST CANCER RISK ASSESSMENT MODELS: WHERE WE STAND AND WHERE WE ARE GOING ; Abstract; Tools to Predict Breast Cancer Risk; Gail Model; Claus Model; BOADICEA; BRCAPRO; IBIS (or Tyrer-Cuzick Model); Future Perspectives; References; Chapter 2 OBESITY AS A CRITICAL ISSUE OF BREAST CANCER DEVELOPMENT ; Abstract; 1. Introduction: Obesity and Breast Cancer; 2. Obesity as a Low-Grade Inflammation; 3. Breast Tumor Microenvironment

3.1. Cancer Immunity and Inflammation3.2. Factors Involved in Obesity-Associated Breast Cancer; 4. Obesity, Breast Cancer and Aromatase; 4.1. Relationship between Obesity and Estrogen; 4.2. Aromatase Overexpression in Estrogen-Responsive Breast Cancer; 4.3. Molecular Regulation of Aromatase in the Postmenopausal Breast; Conclusion and Future Directions; Acknowledgments; References; Chapter 3 HOW TO RETHINK THE CURRENT STANDARDS FOR TREATMENT OF BREAST CANCER AND LONG TERM CARE OF PATIENTS ; Abstract; Introduction; Systemic Regulation of Estrogen Signaling

Interplay between Estrogen Concentrations and ER-Expressions for the Achievement of Appropriate Estrogen SignalingPossibilities for the Restoration of ER Signaling in Apparently ER-Negative Tumor Cells; Local Regulation of Estrogen Synthesis in the Breast; The Question of an Extended Surgery and Adjuvant Radiotherapy for the Treatment of Breast Cancer; Lumpectomy versus Mastectomy; Ipsilateral versus Bilateral Mastectomy; Risk for Development of Disseminated Metastases without a Detectable New Primary or Recurrent Breast Cancer

High Risk Pathology of Early Breast Cancer Does Not Call for the Use of Aggressive TherapyCorrelations between Ageing and the Recurrence Rate of Breast Cancer; Conclusion; References; Chapter 4 MASTECTOMY AND VOLUNTARISM: FROM THE INDIVIDUALIZED SELF TO SOLIDARITY GROUPS IN GREEK WOMEN WITH BREAST CANCER ; Abstract; Introduction; Methodology; Ethical Issues; Broken Bodies, Broken Lives; The Disorganization of the Obvious; A Psychosomatic Experience; To Stand on My Feet, to Beat My Fears; Myself Must Be Well; Limits: The Key Concept; I Ofer to My Self and the Others

Conclusion: Breast Cancer as a Biosocial PatternReferences; INDEX ; Blank Page

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