Recent avenue to cancer prevention / edited by Zsuzsanna Suba.

Print version record.

RECENT AVENUE TO CANCER PREVENTION; RECENT AVENUE TO CANCER PREVENTION; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Acknowledgments; Chapter 1: A Long Way from Hyperestrogenism to Estrogen Deficiency As a Mediator of Cancer Risk in Obesity; Abstract; Introduction; Obesity Related Cancer Risk for Women; A Long Way from Unopposed Hyperestrogenism to Estrogen Deficiency as Mediator of Cancer Risk in Obesity; Correlations between Estrogen Signaling and Lifestyle Factors Affecting Body Weight; References.

Chapter 2: Light Exposure Associated Hormonal Equilibrium is Protective againstCancer RiskAbstract; Introduction; Dysparities between African-American and White American Women in Breast Cancer Incidence and Mortality; Excessive Cancer Risk of African-Americans and Dark Skinned Immigrants in Northern Geographic Regions; Correlations between Excessive Melatonin Level, Other Endocrine Alterations and Cancer Risk; Correlations among Light Exposure, Melatonin Level and Breast Cancer Risk; Review of Melatonin Use As Nutritional Supplement; Conclusion; References.

Chapter 3: Sexual Dimorphism in Obesity Related Cancer RiskAbstract; Introduction; Hormonal and Metabolic Disorders As Links between Obesity and Cancer Risk in Males and Females; Correlations among Obesity Associated Insulin Resistance, Hyperinsuinism and Cancer Risk; Does Excessive or Defective Estrogen Signaling Mediate Strong Cancer Risk in Obese Patients?; Controversial Results on Obesity Related Overall Cancer Incidence in Men and Women; Differences in the Gender Related Overall Cancer Risk of Obesity Defined by Geographic Regions.

Race Related Disparities in Obesity Associated Cancer Risk in Men and WomenGender Related Differences in the Obesity Associated Risk for Individual Cancer Sites; Paradigm of Extreme Differences in Breast Cancer Incidence between Obese Men and Women; Conclusion; References; Chapter 4: Recovery of Estrogen Level in Obese Women Is Preventive against Cancer; Abstract; Introduction; Pathogenetic Mechanisms As Links between Obesity and Breast Cancer Risk; Protective Effects of Estrogen against Obesity and Obesity Associated Alterations.

Correlations between Grade and Distribution of Obesity and Insulin ResistanceLifelong Changes in the Estrogen Level of Women and Their Relation to Obesity and Breast Cancer Risk; Exogenous Hormone Use for Prevention and Treatment of Breast Cancer; Conclusion; References; Chapter 5: Estrogen Receptors Are Pivotal Regulators of Glucose Uptake and Energy Expenditure; Abstract; Introduction; Role of Estradiol and Its Receptors in the Regulation of Cellular Glucose Uptake and Energy Homeostasis.

This work presents some recent clinical, epidemiological and experimental data on the cancer preventive effect of healthy hormonal equilibrium. Insulin resistance-associated overproduction of peptide hormones, such as growth hormone, insulin and insulin-like growth factors, interacting simply with cell membrane receptors, have a proven tumor inducing capacity. Another group of hormones, including estrogens, thyroids and vitamin D, has both genomic intranuclear and non-genomic membrane-associated receptor signaling, thus they have complex roles in all basic cellular functions. Recent results su.

Includes bibliographical references and index.

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