Transfusion medicine and patient safety / Giustina de Silvestro, Arianna Veronesi, Maria Vicarioto.

Includes bibliographical references and index.

Introduction; 1 Basics of transfusion medicine; 1.1 The ABO and Rh blood group systems; 1.2 Other blood group systems; 1.2.1 The MNSs system; 1.2.2 The P system; 1.2.3 The Lutheran system; 1.2.4 The Kell system; 1.2.5 The Lewis system; 1.2.6 The Duffy system; 1.2.7 The Kidd system; 1.2.8 The Diego system; 1.2.9 The Xg-a system; 1.2.10 The Dombrock system; 1.2.11 The Colton system; 1.2.12 The Chido/Rodgers system; 1.2.13 The Cromer system; 1.2.14 The I/i system; 1.3 Natural and immune antibodies; 1.4 Transfusion guidelines; 1.4.1 Indications for the transfusion of concentrated red blood cells.

1.4.2 Indications for the transfusion of platelet concentrates1.4.3 Indications for the transfusion of fresh frozen plasma; 1.4.4 Indications for the transfusion of leukodepleted blood components; 1.4.5 Indications for the transfusion of irradiated blood components; 1.4.6 Indications for granulocyte transfusions; 1.4.7 Virus-inactivated blood components; 1.4.8 Complications of transfusion therapy; 2 The transfusion process; 2.1 Blood donation; 2.2 Donating multiple blood components; 2.3 Preparation of blood and blood components; 2.4 The immunohematology laboratory.

2.5 The immunohematology laboratory2.5.1 Studying the Rh system; 2.5.2 Detecting allo-antibodies to red cell antigens; 2.6 Transfusion request forms and the administration of blood and blood components; 3 Automation and computerization of the transfusion process; 3.1 Automation as a safety factor; 3.2 Computerization of the transfusion process: from donor to patient; 3.3 The computerized transfusion network; 3.4 Hemovigilance; 3.5 What can be improved in the future?; 4 Biological validation of blood components; 4.1 Molecular and serological methods; 4.1.1 Serological investigations.

4.1.2 Molecular investigations4.1.3 Structure of the DNA; 4.1.4 Real-time PCR; 4.1.5 PCR-TMA; 4.2 Decision-making and the quality system; 4.3 Risk management versus patient safety: medicolegal considerations; 5 Error in transfusion medicine; Index.

Print version record.

Transfusional medicine is a young discipline, whereas the AB0 system was discovered only at the beginning of the last century, and that the neonatal haemolytic disease has been described in the middle of the 20th century. However, the evolution of technologies and diagnostic systems for immunohaematology, especially in recent decades, has been very intense and fast, and today the transfusional process, from the donation of blood until the transfusion of the patient, is perfectly controlled. This volume aims to highlight the main critical moments in which the operator must pay close attention,

English.

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