Biophotonics in pathology : pathology at the crossroads / edited by Stanley Cohen.

Includes indexes.

Title Page -- Preface -- Contents -- Physics and Engineering Aspects of Cell and Tissue Imaging Systems: Microscopic Devices and Computer Assisted Diagnosis -- Advanced Methods in Fluorescence Microscopy -- Spectral Imaging in Preclinical Research and Clinical Pathology -- Automated Image Interpretation and Computer-Assisted Diagnostics -- Optical Coherence Tomography for Rapid Tissue Screening and Directed Histological Sectioning -- Nuclear Morphology Measurements with Angle-Resolved Low Coherence Interferometry for Application to Cell Biology and Early Cancer Detection -- Magnetic Resonance Microscopy -- Impedance Measurements in the Biomedical Sciences -- Raman Scattering in Pathology -- Real-Time Pathology Through In Vivo Microscopy -- Biophotonics Techniques for Structural and Functional Imaging, In Vivo -- Lensfree Computational Microscopy Tools for Cell and Tissue Imaging at the Point-of-Care and in Low-Resource Settings -- The Evolution of Anatomic Pathology: New Strategies and Emerging Trends -- Subject Index -- Author Index.

Photonics is a term often used in relation to light-based circuits, but it is actually more inclusive, including the generation, emission, transmission, modulation and signal processing of light. Biophotonics is therefore a term which can be used to describe the development and application of optical techniques for the study of biological molecules, cells and tissues. This book presents some of the most promising new image-based and related technologies which have evolved in the last few years for the study, visualization, characterisation and analysis of abnormal cells and tissues, and discusses their current and potential applications in experimental pathology and clinical pathological diagnosis. The book contains more than a dozen papers contributed by experts in the field, and the technology is described in a manner accessible to an audience of pathologists, cell biologists and biochemists as well as biomedical engineers. Subjects covered include: advanced methods in fluorescence microscopy, automated image interpretation and computer-assisted diagnostics, magnetic resonance microscopy, impedence measurements in the biomedical sciences and raman scattering in pathology, among others. There is an increasing convergence of radiology and pathology, and although this book has been written from the perspective of pathology, it demonstrates a confluence of methodologies similar to those applied in radiology with morphological analysis at the cellular and tissue level, and will also be of interest to radiologists, as well as to other scientists and engineers working in overlapping areas.

Includes bibliographical references and index.

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